Olivopontocerebellar Atrophy Questions & Answers

Updated: Dec 17, 2018
  • Author: Sombat Muengtaweepongsa, MD, MSc; Chief Editor: Selim R Benbadis, MD  more...
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Questions & Answers

Overview

What is olivopontocerebellar atrophy (OPCA)?

What is the Greenfield classification of olivopontocerebellar atrophy (OPCA)?

What is the Konigsmark and Weiner classification of olivopontocerebellar atrophy (OPCA)?

Which spinocerebellar ataxias (SCAs) are considered olivopontocerebellar atrophies (OPCAs)?

How is sporadic olivopontocerebellar atrophy (OPCA) classified?

How is genetic olivopontocerebellar atrophy (OPCA) classified?

What is the pathophysiology of olivopontocerebellar atrophy (OPCA)?

What is the prevalence of olivopontocerebellar atrophy (OPCA)?

What is the mortality and morbidity associated with olivopontocerebellar atrophy (OPCA)?

Which patient groups have the highest prevalence of olivopontocerebellar atrophy (OPCA)?

Presentation

Which clinical history findings are characteristic of olivopontocerebellar atrophy (OPCA)?

What are the signs and symptoms of olivopontocerebellar atrophy (OPCA)?

How does the clinical presentation of olivopontocerebellar atrophy (OPCA) vary among subtypes?

What causes olivopontocerebellar atrophy (OPCA)?

What causes infantile olivopontocerebellar atrophy (OPCA)?

What are the spinocerebellar ataxia (SCA) equivalents for olivopontocerebellar atrophy (OPCA)?

What are the autosomal dominant cerebellar atrophy (ADCA) equivalents for olivopontocerebellar atrophy (OPCA)?

DDX

What are the differential diagnoses for Olivopontocerebellar Atrophy?

Workup

How is paraneoplastic cerebellar degeneration differentiated from olivopontocerebellar atrophy (OPCA)?

What is the role of vitamin E measurement in the workup of olivopontocerebellar atrophy (OPCA)?

What is the role of MRI in the workup of olivopontocerebellar atrophy (OPCA)?

What is the role of genetic testing in the workup of olivopontocerebellar atrophy (OPCA)?

What is the role of sleep studies in the workup of olivopontocerebellar atrophy (OPCA)?

What is the role of nerve conduction studies and evoked potentials in the workup of olivopontocerebellar atrophy (OPCA)?

What is the role of EEG in the workup of olivopontocerebellar atrophy (OPCA)?

Which histologic findings are characteristic of olivopontocerebellar atrophy (OPCA)?

Treatment

How is olivopontocerebellar atrophy (OPCA) treated?

What is the role of surgery in the treatment of olivopontocerebellar atrophy (OPCA)?

Which specialist consultations are beneficial to patients with olivopontocerebellar atrophy (OPCA)?

Which dietary modifications are used in the treatment of olivopontocerebellar atrophy (OPCA)?

Which activity modifications are used in the treatment of olivopontocerebellar atrophy (OPCA)?

Medications

What is the role of medications in the treatment of olivopontocerebellar atrophy (OPCA)?

Which medications in the drug class Antianxiety Agent are used in the treatment of Olivopontocerebellar Atrophy?

Which medications in the drug class Antihypertensive agents are used in the treatment of Olivopontocerebellar Atrophy?

Which medications in the drug class Dopaminergic agents are used in the treatment of Olivopontocerebellar Atrophy?

Follow-up

What are the possible complications of olivopontocerebellar atrophy (OPCA)?

What is the prognosis of olivopontocerebellar atrophy (OPCA)?