Dissection Syndromes Medication

Updated: Dec 08, 2015
  • Author: Chelsea S Kidwell, MD; Chief Editor: Helmi L Lutsep, MD  more...
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Medication

Medication Summary

The goals of pharmacotherapy are to prevent complications and to reduce morbidity.

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Anticoagulants

Class Summary

These agents are used to prevent thromboembolisms.

Heparin

Augments activity of antithrombin III and prevents conversion of fibrinogen to fibrin; does not actively lyse but is able to inhibit further thrombogenesis; prevents reaccumulation of a clot after spontaneous fibrinolysis.

Warfarin (Coumadin)

Interferes with hepatic synthesis of vitamin K–dependent coagulation factors; used for prophylaxis and treatment of venous thrombosis, pulmonary embolism, and thromboembolic disorders.

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Antiplatelet agents

Class Summary

These agents prevent thromboembolism.

Aspirin (Anacin, Ascriptin, Bayer Aspirin, Bayer Buffered Aspirin)

Inhibits prostaglandin synthesis, which prevents formation of platelet-aggregating thromboxane A-2.

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