Addison Disease Guidelines

Updated: Jan 13, 2022
  • Author: George T Griffing, MD; Chief Editor: Romesh Khardori, MD, PhD, FACP  more...
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Guidelines Summary

Recommendations from the French endocrinology society and the French pediatric endocrinology society discuss the management, for adults and children, of primary and secondary adrenal insufficiency. Among the recommendations, the societies state that in cases of persistent doubt regarding the presence of secondary adrenal insufficiency in adults, adolescents, and children over age 2 years, an insulin hypoglycemia test should be administered. The initial test to find the cause of primary adrenal insufficiency should be measurement of anti-21-hydroxylase antibodies. Negative autoantibody tests should be followed by an adrenal computed tomography (CT) scan; it is recommended that in young males, an assay for very-long-chain fatty acids then be performed. [52]