Neurological Manifestations of Thyroid Disease Treatment & Management

Updated: Sep 18, 2017
  • Author: Gabriel Bucurescu, MD, MS; Chief Editor: Nicholas Lorenzo, MD, MHA, CPE  more...
  • Print
Treatment

Medical Care

Neurologic manifestations in thyroid disease generally develop slowly. They are diagnosed months or years after initial endocrine problems. Patients seek care after developing characteristic systemic signs and symptoms.

Polyneuropathy is rarely the initial manifestation of undetected hypothyroidism. Metastatic thyroid carcinoma rarely presents as an initial brain metastatic lesion.

Chorea-ballism has been reported sporadically. Chorea has been associated with elevated levels of antithyroid antibodies, with the symptoms responding to oral steroid treatment.

Interestingly, one study reports that mild hypothyroidism is associated with better survival of ambulatory elderly patients after acute stroke. [22]

Several reports of intracranial vascular disease (arterial occlusion, superior sagittal sinus thrombosis, cerebral vein thrombosis) have been reported associated with both hypothyroidism and hyperthyroidism. However, the patients had multiple pathologies, and a clear correlation with thyroid disease is difficult to establish. [23, 24, 25]

Next:

Surgical Care

Surgery is indicated in the treatment of thyroid masses and large goiters.

Previous
Next:

Consultations

The following consultations may be warranted:

  • Internal medicine/endocrinologist

  • Head and neck surgeon

  • Nuclear medicine specialist

  • Radiation oncologist

  • Pathologist

Previous
Next:

Diet

Iodine deficiency is not widespread in the United States, although immigrants from areas of endemic deficiency may require dietary consultation. Pregnant women may require more careful screening.

Previous
Next:

Activity

No restrictions are recommended typically.

Previous