Toxic Neuropathy Questions & Answers

Updated: Dec 06, 2017
  • Author: Jonathan S Rutchik, MD, MPH, FACOEM; Chief Editor: Tarakad S Ramachandran, MBBS, MBA, MPH, FAAN, FACP, FAHA, FRCP, FRCPC, FRS, LRCP, MRCP, MRCS  more...
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Questions & Answers

Overview

What causes toxic neuropathy?

What are the signs and symptoms of toxic neuropathy?

How is toxic neuropathy diagnosed?

Which medications are used in the treatment of toxic neuropathy?

What is toxic neuropathy?

What is the pathophysiology of toxic neuropathy?

What is the prevalence of toxic neuropathy?

Presentation

Which clinical history findings are characteristic of toxic neuropathy?

Which physical findings are characteristic of toxic neuropathy?

Which drugs cause toxic neuropathy?

Which industrial chemicals cause toxic neuropathy?

What is the role of carbon disulfide in the etiology of toxic neuropathy?

What is the role of EtO in the etiology of toxic neuropathy?

What is the role of mercury in the etiology of toxic neuropathy?

What is the role of lead in the etiology of toxic neuropathy?

What is the role of xylene in the etiology of toxic neuropathy?

What is the role of PERC in the etiology of toxic neuropathy?

What is the role of TCE in the etiology of toxic neuropathy?

DDX

What are the differential diagnoses for Toxic Neuropathy?

Workup

What is the role of lab tests in the workup of toxic neuropathy?

What is the role of EMG and NCV in the workup of toxic neuropathy?

Which neurophysiologic findings are characteristic of ethylene-related toxic neuropathy?

Which neurophysiologic findings are characteristic of mercury-related toxic neuropathy?

Which neurophysiologic findings are characteristic of xylene-related toxic neuropathy?

Which histologic findings are characteristic of toxic neuropathy?

Treatment

How is toxic neuropathy treated?

Which specialist consultations are beneficial to patients with toxic neuropathy?

Which dietary modifications are used in the treatment of toxic neuropathy?

Follow-up

What is included in the long-term monitoring of patients with toxic neuropathy?

What is the prognosis of toxic neuropathy?

What is included in patient education about toxic neuropathy?