Neurologic Manifestations of Incontinentia Pigmenti Treatment & Management

Updated: Dec 11, 2018
  • Author: Celia H Chang, MD; Chief Editor: Amy Kao, MD  more...
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Treatment

Medical Care

No specific treatment is available for incontinentia pigment. [14]

  • The stage 1 lesions should be left intact and kept clean.

  • Kaya et al reported almost complete resolution of stage 1 lesions in 5 days after applying diflucortolone valerate .1% and chlorquinaldol 1% twice a day. They thought the rapid resolution of the lesions was due to response of the eosinophilic inflammation to the topical steroids. [15]

  • Meticulous dental care is very important.

  • Lin et al performed intravitreal injection of an anti-VEGF agent (bevacizumab 1.25 mg/.05 mL) in a patient who had failed laser photocoagulation therapy. Five days after the injection, the neovascular frond became avascular and was successfully removed surgically. Unfortunately, the eye subsequently developed a persistent pupillary membrane, another episode of retinal detachment, and rubeosis iridis with neovascular glaucoma. [16]

Next:

Consultations

See the list below:

  • Ophthalmologist

  • Dentist

  • Geneticist

  • Neurologist, only if neurologic abnormalities are present

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