Diabetes Insipidus Questions & Answers

Updated: Mar 18, 2020
  • Author: Romesh Khardori, MD, PhD, FACP; Chief Editor: George T Griffing, MD  more...
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Questions & Answers

Overview

How is diabetes insipidus (DI) defined and characterized?

How does diabetes insipidus (DI) present?

What is the most common form of diabetes insipidus (DI) and what patterns may be exhibited?

What are the signs of diabetes insipidus (DI) in infants?

What is the presentation of diabetes insipidus (DI) in children?

What is the presentation of diabetes insipidus (DI) if the anterior pituitary or hypothalamic centers are damaged?

Which physical findings suggest diabetes insipidus (DI)?

Which lab tests are performed to confirm the diagnosis of diabetes insipidus (DI)?

When are water deprivation and pituitary studies indicated in the diagnosis of diabetes insipidus (DI)?

How is diabetes insipidus (DI) treated?

What are pharmacologic therapies in the treatment of diabetes insipidus (DI)?

How is diabetes insipidus (DI) defined?

How is central diabetes insipidus (DI) characterized?

How is nephrogenic diabetes insipidus (DI) characterized?

What are gestational diabetes insipidus (DI) and primary polydipsia?

What are the hereditary types of diabetes insipidus (DI)?

What is the pharmacologic treatment of diabetes insipidus (DI)?

What is the role of water balance maintenance in the pathogenesis of diabetes insipidus (DI)?

What is the role of arginine vasopressin (AVP) in the pathogenesis of diabetes insipidus (DI)?

What are the vasoconstrictor effects of arginine vasopressin (AVP) in patients with diabetes insipidus (DI)?

What is the role of antidiuretic hormone (ADH) in the pathogenesis of diabetes insipidus (DI)?

What is the role of a decreased extracellular fluid (ECF) volume in the pathogenesis of diabetes insipidus (DI)?

What causes diabetes insipidus (DI)?

What are the causes of central diabetes insipidus (DI)?

What is the pathogenesis of idiopathic central diabetes insipidus (DI)?

What is the evidence of an autoimmune etiology of idiopathic central diabetes insipidus (DI)?

What monitoring should be performed for patients with idiopathic central diabetes insipidus (DI)?

What is the role of human chorionic gonadotropin (hCG) in the early diagnosis of germinoma in diabetes insipidus (DI)?

Which primary intracranial tumors cause diabetes insipidus (DI)?

What is the incidence of diabetes insipidus (DI) following neurosurgery?

What is postoperative polyuria and is it indicative of diabetes insipidus (DI)?

What are the risk factors for diabetes insipidus (DI)?

What is the incidence of hereditary central diabetes insipidus (DI)?

What are the genetic causes of diabetes insipidus (DI)?

What are the non-genetic causes of central diabetes insipidus (DI)?

Does targeted temperature management (TTM) of cardiac arrest increase the risk of developing central diabetes insipidus (DI)?

What are the causes of nephrogenic diabetes insipidus (DI) in adults?

What are the less common causes of nephrogenic diabetes insipidus (DI)?

Which drugs can cause diabetes insipidus (DI)?

What are the genetic causes of nephrogenic diabetes insipidus (DI)?

What is the prevalence of diabetes insipidus (DI)?

What is the prognosis of diabetes insipidus (DI)?

Presentation

What are the patterns of central diabetes insipidus (DI)?

What are the signs and symptoms of diabetes insipidus (DI)?

What are the signs of diabetes insipidus (DI) in infants?

What are the signs and symptoms of diabetes insipidus (DI) in children?

What is the risk of diabetes insipidus (DI) in pregnancy?

What is the most sensitive indicator of water balance in diabetes insipidus (DI)?

What is adipsic diabetes insipidus (DI)?

What are symptoms and signs of anterior pituitary dysfunction in diabetes insipidus (DI)?

Which physical findings suggest diabetes insipidus (DI)?

DDX

What are the differential diagnoses for Diabetes Insipidus?

Workup

Which lab tests are performed to confirm the diagnosis of diabetes insipidus (DI)?

How is diabetes insipidus (DI) diagnosed?

What is the role of water deprivation testing in the workup of diabetes insipidus (DI)?

Which water deprivation test findings are diagnostic for central or nephrogenic diabetes insipidus (DI)?

What causes misleading water deprivation test results in the workup of diabetes insipidus (DI)?

Which pituitary study findings suggest diabetes insipidus (DI)?

What is the role of pituitary studies in the workup of diabetes insipidus (DI)?

What is the role of imaging studies in the workup of diabetes insipidus (DI)?

Treatment

What are the options for fluid replacement in patients with diabetes insipidus (DI)?

What is the role of drug therapy in the treatment of diabetes insipidus (DI)?

How should patients be monitored during and following treatment of diabetes insipidus (DI)?

What are the dietary restrictions in the treatment of diabetes insipidus (DI)?

What precautions should patients with diabetes insipidus (DI) take when traveling?

What postoperative monitoring should be performed to screen for diabetes insipidus (DI)?

When are specialist consultations required for diabetes insipidus (DI)?

Medications

How does the treatment for diabetes insipidus (DI) vary?

Which medications in the drug class Diuretics, Potassium-Sparing are used in the treatment of Diabetes Insipidus?

Which medications in the drug class Nonsteroidal Anti-inflammatory Agents (NSAIDs) are used in the treatment of Diabetes Insipidus?

Which medications in the drug class Diuretics, Thiazide are used in the treatment of Diabetes Insipidus?

Which medications in the drug class Anticonvulsants are used in the treatment of Diabetes Insipidus?

Which medications in the drug class Antidiabetics, Sulfonylureas are used in the treatment of Diabetes Insipidus?

Which medications in the drug class Vasopressin-Related Hormones are used in the treatment of Diabetes Insipidus?