Neurologic Manifestations of Xeroderma Pigmentosum Treatment & Management

Updated: Apr 01, 2015
  • Author: Peter Hedera, MD, PhD; Chief Editor: Amy Kao, MD  more...
  • Print
Treatment

Medical Care

See the list below:

  • Skin hypersensitivity and skin cancer should be treated by a dermatologist. [10]
  • Neurologic care is mostly supportive. Seizures can be treated like other complex partial seizures with secondary generalization. Spasticity is usually mild. If it interferes with mobility, baclofen or botulinum toxin (BOTOX®) injection may be beneficial.
Next:

Consultations

Every patient with xeroderma pigmentosum needs to be monitored regularly by a dermatologist and ophthalmologist. Consultation with a geneticist may help to differentiate xeroderma pigmentosum from other related conditions, such as Cockayne syndrome and progeria.

Previous
Next:

Activity

Patients must avoid the sun to protect their skin. If sun exposure cannot be entirely avoided, patients should wear long sleeves, use sunscreen with SPF 50, and wear dark glasses. Some families reverse their day/night cycle to eliminate sun exposure entirely.

Previous