Mobius Syndrome Medication

Updated: Oct 04, 2018
  • Author: Cheryl Ann Palmer, MD; Chief Editor: Amy Kao, MD  more...
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Medication Summary

With few exceptions, pharmacologic intervention in patients with Möbius syndrome is used only for symptomatic treatment. As previously mentioned, patients with Möbius syndrome may be predisposed to infections, such as pulmonary infections resulting from aspiration pneumonia, and otitis media caused by structural anomalies of the ear. Vigilance and a low threshold for treatment are required. Antibiotics used in the treatment of infectious complications include amoxicillin and trimethoprim and sulfamethoxazole (TMP-SMZ).


Antibiotics, Other

Class Summary

Proper antibiotic therapy should be started in the event of infections such as pneumonia or otitis media.

Amoxicillin (Moxatag)

Amoxicillin is an ampicillin analogue with broad-spectrum bactericidal activity against many gram-positive and gram-negative organisms.

Trimethoprim and sulfamethoxazole (Bactrim, Bactrim DS, Septra DS)

TMP-SMZ is a synthetic, broad-spectrum antibacterial combination. It inhibits bacterial synthesis of dihydrofolic acid by competing with para-aminobenzoic acid (PABA), inhibiting bacterial growth.