Choroidal Neovascularization (CNV) Clinical Presentation

Updated: Dec 06, 2021
  • Author: Lihteh Wu, MD; Chief Editor: Andrew A Dahl, MD, FACS  more...
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Presentation

History

History may include the following:

  • Painless loss of vision

  • Metamorphopsia

  • Paracentral or central scotoma

  • Apparent change in image size

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Physical

Physical findings may include the following:

  • Subretinal blood

  • Subretinal fluid

  • Lipid exudation

  • Retinal pigment epithelial detachment

  • Subretinal fibrosis (disciform scar)

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Causes

Virtually any pathologic process that involves the RPE and damages the Bruch membrane can be complicated by CNV.

In a study examining the relationship of smoking to CNV secondary to presumed ocular histoplasmosis syndrome (POHS), Chheda et al found that the risk of smokers having CNV secondary to POHS is three times higher than that of nonsmokers. The risk increased with age and decreased with increasing level of educational information. [22]

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