Choroidal Neovascularization (CNV) Clinical Presentation

Updated: Jul 27, 2020
  • Author: Lihteh Wu, MD; Chief Editor: Andrew A Dahl, MD, FACS  more...
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Presentation

History

History may include the following:

  • Painless loss of vision

  • Metamorphopsia

  • Paracentral or central scotoma

  • Apparent change in image size

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Physical

See the list below:

  • Subretinal blood

  • Subretinal fluid

  • Lipid exudation

  • Retinal pigment epithelial detachment

  • Subretinal fibrosis (disciform scar)

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Causes

Virtually any pathologic process that involves the RPE and damages the Bruch membrane can be complicated by CNV.

In a study examining the relationship of smoking to CNV secondary to presumed ocular histoplasmosis syndrome (POHS), Chheda et al found that the risk of smokers having CNV secondary to POHS is 3 times higher than that of nonsmokers. The risk increased with age and decreased with increasing level of educational information. [22]

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