Bacterial Conjunctivitis (Pink Eye) Questions & Answers

1. Hashmi MF, Gurnani B, Benson S. Conjunctivitis. StatPearls. 2022 Jan. [QxMD MEDLINE Link]. [Full Text].

2. Shields T, Sloane PD. A comparison of eye problems in primary care and ophthalmology practices. Fam Med. 1991 Sep-Oct. 23 (7):544-6. [QxMD MEDLINE Link].

3. Udeh BL, Schneider JE, Ohsfeldt RL. Cost effectiveness of a point-of-care test for adenoviral conjunctivitis. Am J Med Sci. 2008 Sep. 336 (3):254-64. [QxMD MEDLINE Link].

4. van Weert HC, Tellegen E, Ter Riet G. A new diagnostic index for bacterial conjunctivitis in primary care. A re-derivation study. Eur J Gen Pract. 2014 Sep. 20 (3):202-8. [QxMD MEDLINE Link].

5. Pippin MM, Le JK. Bacterial Conjunctivitis. StatPearls. 2022 Jan. [QxMD MEDLINE Link]. [Full Text].

6. Smith AF, Waycaster C. Estimate of the direct and indirect annual cost of bacterial conjunctivitis in the United States. BMC Ophthalmol. 2009 Nov 25. 9:13. [QxMD MEDLINE Link].

7. Narayana S, McGee S. Bedside Diagnosis of the 'Red Eye': A Systematic Review. Am J Med. 2015 Nov. 128 (11):1220-1224.e1. [QxMD MEDLINE Link].

8. Jefferis J, Perera R, Everitt H, van Weert H, Rietveld R, Glasziou P, et al. Acute infective conjunctivitis in primary care: who needs antibiotics? An individual patient data meta-analysis. Br J Gen Pract. 2011 Sep. 61 (590):e542-8. [QxMD MEDLINE Link].

9. Rietveld RP, ter Riet G, Bindels PJ, Schellevis FG, van Weert HC. Do general practitioners adhere to the guideline on infectious conjunctivitis? Results of the Second Dutch National Survey of General Practice. BMC Fam Pract. 2007 Sep 16. 8:54. [QxMD MEDLINE Link].

10. Isenberg SJ, Apt L, Valenton M, Del Signore M, Cubillan L, Labrador MA. A controlled trial of povidone-iodine to treat infectious conjunctivitis in children. Am J Ophthalmol. 2002 Nov. 134(5):681-8. [QxMD MEDLINE Link].

11. Jeng BH, Gritz DC, Kumar AB, Holsclaw DS, Porco TC, Smith SD, et al. Epidemiology of ulcerative keratitis in Northern California. Arch Ophthalmol. 2010 Aug. 128 (8):1022-8. [QxMD MEDLINE Link].

12. Høvding G. Acute bacterial conjunctivitis. Acta Ophthalmol. 2008 Feb. 86 (1):5-17. [QxMD MEDLINE Link].

13. Rapoza PA, Quinn TC, Kiessling LA, Taylor HR. Epidemiology of neonatal conjunctivitis. Ophthalmology. 1986 Apr. 93(4):456-61. [QxMD MEDLINE Link].

14. Bourne RR, Stevens GA, White RA, Smith JL, Flaxman SR, Price H, et al. Causes of vision loss worldwide, 1990-2010: a systematic analysis. Lancet Glob Health. 2013 Dec. 1 (6):e339-49. [QxMD MEDLINE Link].

15. Laspina F, Samudio M, Cibils D, Ta CN, Fariña N, Sanabria R, et al. Epidemiological characteristics of microbiological results on patients with infectious corneal ulcers: a 13-year survey in Paraguay. Graefes Arch Clin Exp Ophthalmol. 2004 Mar. 242 (3):204-9. [QxMD MEDLINE Link].

16. Sirikul T, Prabriputaloong T, Smathivat A, Chuck RS, Vongthongsri A. Predisposing factors and etiologic diagnosis of ulcerative keratitis. Cornea. 2008 Apr. 27 (3):283-7. [QxMD MEDLINE Link].

17. Leck AK, Thomas PA, Hagan M, Kaliamurthy J, Ackuaku E, John M, et al. Aetiology of suppurative corneal ulcers in Ghana and south India, and epidemiology of fungal keratitis. Br J Ophthalmol. 2002 Nov. 86 (11):1211-5. [QxMD MEDLINE Link].

18. Lichtenstein SJ, Rinehart M, Levofloxacin Bacterial Conjunctivitis Study Group. Efficacy and safety of 0.5% levofloxacin ophthalmic solution for the treatment of bacterial conjunctivitis in pediatric patients. J AAPOS. 2003 Oct. 7 (5):317-24. [QxMD MEDLINE Link].

19. Sheikh A, Hurwitz B, van Schayck CP, McLean S, Nurmatov U. Antibiotics versus placebo for acute bacterial conjunctivitis. Cochrane Database Syst Rev. 2012 Sep 12. 9:CD001211. [QxMD MEDLINE Link].

20. Ullman S, Roussel TJ, Culbertson WW, Forster RK, Alfonso E, Mendelsohn AD, et al. Neisseria gonorrhoeae keratoconjunctivitis. Ophthalmology. 1987 May. 94(5):525-31. [QxMD MEDLINE Link].

21. Schachter J, Lum L, Gooding CA, Ostler B. Pneumonitis following inclusion blennorrhea. J Pediatr. 1975 Nov. 87(5):779-80. [QxMD MEDLINE Link].

22. Horner C, Wilcox M, Barr B, Hall D, Hodgson G, Parnell P, et al. The longitudinal prevalence of MRSA in care home residents and the effectiveness of improving infection prevention knowledge and practice on colonisation using a stepped wedge study design. BMJ Open. 2012. 2 (1):e000423. [QxMD MEDLINE Link].

23. Rietveld RP, ter Riet G, Bindels PJ, Sloos JH, van Weert HC. Predicting bacterial cause in infectious conjunctivitis: cohort study on informativeness of combinations of signs and symptoms. BMJ. 2004 Jul 24. 329 (7459):206-10. [QxMD MEDLINE Link].

24. Alfonso EC, Cantu-Dibildox J, Munir WM, Miller D, O'Brien TP, Karp CL, et al. Insurgence of Fusarium keratitis associated with contact lens wear. Arch Ophthalmol. 2006 Jul. 124 (7):941-7. [QxMD MEDLINE Link].

25. Borkar DS, Acharya NR, Leong C, Lalitha P, Srinivasan M, Oldenburg CE, et al. Cytotoxic clinical isolates of Pseudomonas aeruginosa identified during the Steroids for Corneal Ulcers Trial show elevated resistance to fluoroquinolones. BMC Ophthalmol. 2014 Apr 24. 14:54. [QxMD MEDLINE Link].

26. Srinivasan M, Mascarenhas J, Rajaraman R, Ravindran M, Lalitha P, O'Brien KS, et al. The steroids for corneal ulcers trial (SCUT): secondary 12-month clinical outcomes of a randomized controlled trial. Am J Ophthalmol. 2014 Feb. 157 (2):327-333.e3. [QxMD MEDLINE Link].

27. Srinivasan M, Mascarenhas J, Rajaraman R, Ravindran M, Lalitha P, Ray KJ, et al. Visual recovery in treated bacterial keratitis. Ophthalmology. 2014 Jun. 121 (6):1310-1. [QxMD MEDLINE Link].

28. Hammerschlag MR, Cummings C, Roblin PM, Williams TH, Delke I. Efficacy of neonatal ocular prophylaxis for the prevention of chlamydial and gonococcal conjunctivitis. N Engl J Med. 1989 Mar 23. 320(12):769-72. [QxMD MEDLINE Link].

29. [Guideline] AAO Cornea/External Disease PPP Panel, Hoskins Center for Quality Eye Care. Conjunctivitis PPP. ONE Network. Available at http://www.aao.org/preferred-practice-pattern/conjunctivitis-ppp--2013. 2013;

30. Sheikh A, Hurwitz B, van Schayck CP, McLean S, Nurmatov U. Antibiotics versus placebo for acute bacterial conjunctivitis. Cochrane Database Syst Rev. 2012 Sep 12. 9:CD001211. [QxMD MEDLINE Link].

31. Asbell PA, Colby KA, Deng S, McDonnell P, Meisler DM, Raizman MB, et al. Ocular TRUST: nationwide antimicrobial susceptibility patterns in ocular isolates. Am J Ophthalmol. 2008 Jun. 145 (6):951-958. [QxMD MEDLINE Link].

32. Asbell PA, Sanfilippo CM, Pillar CM, DeCory HH, Sahm DF, Morris TW. Antibiotic Resistance Among Ocular Pathogens in the United States: Five-Year Results From the Antibiotic Resistance Monitoring in Ocular Microorganisms (ARMOR) Surveillance Study. JAMA Ophthalmol. 2015 Dec. 133 (12):1445-54. [QxMD MEDLINE Link].

33. O'Brien TP. Besifloxacin ophthalmic suspension, 0.6%: a novel topical fluoroquinolone for bacterial conjunctivitis. Adv Ther. 2012 Jun. 29(6):473-90. [QxMD MEDLINE Link].

34. Aoki R, Fukuda K, Ogawa M, Ikeno T, Kondo H, Tawara A, et al. Identification of Causative Pathogens in Eyes with Bacterial Conjunctivitis by Bacterial Cell Count and Microbiota Analysis. Ophthalmology. 2012 Dec 12. [QxMD MEDLINE Link].

35. Tabbara KF, Hyndiuk RA. Infections of the Eye. Boston, Mass: Little, Brown and Company; 1996.

36. Deschênes J, Blondeau J. Besifloxacin in the management of bacterial infections of the ocular surface. Can J Ophthalmol. 2015 Jun. 50 (3):184-91. [QxMD MEDLINE Link].

37. Kitatani F, Fujimoto S, Asahi T, Konishiike J, Sera Y. [Clinical study on rifampicin applied every other day for severe cavitary pulmonary tuberculosis (author's transl)]. Kekkaku. 1974 May. 49 (5):133-8. [QxMD MEDLINE Link].

38. Deschênes J, Blondeau J. Besifloxacin in the management of bacterial infections of the ocular surface. Can J Ophthalmol. 2015 Jun. 50 (3):184-91. [QxMD MEDLINE Link].

39. Garnock-Jones KP. Azithromycin 1.5% ophthalmic solution: in purulent bacterial or trachomatous conjunctivitis. Drugs. 2012 Feb 12. 72 (3):361-73. [QxMD MEDLINE Link].

Karen K Yeung, OD, FAAO Senior Optometrist, UCLA Arthur Ashe Student Health and Wellness Center; Clinical Assistant Professor, College of Optometry, Western University of Health Sciences

Karen K Yeung, OD, FAAO is a member of the following medical societies: American Academy of Optometry

Disclosure: Nothing to disclose.

Barry A Weissman, OD, PhD, FAAO Retired Professor of Optometry, Southern California College of Optometry at Marshall B Ketchum University; Professor Emeritus of Ophthalmology, Stein Eye Institute, University of California, Los Angeles, David Geffen School of Medicine

Barry A Weissman, OD, PhD, FAAO is a member of the following medical societies: American Academy of Optometry, American Optometric Association, California Optometric Society, International Society for Contact Lens Research

Disclosure: Nothing to disclose.

Francisco Talavera, PharmD, PhD Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Received salary from Medscape for employment. for: Medscape.

Andrew A Dahl, MD, FACS Assistant Professor of Surgery (Ophthalmology), New York College of Medicine (NYCOM); Director of Residency Ophthalmology Training, The Institute for Family Health and Mid-Hudson Family Practice Residency Program; Staff Ophthalmologist, Telluride Medical Center

Andrew A Dahl, MD, FACS is a member of the following medical societies: American Academy of Ophthalmology, American College of Surgeons, American Intraocular Lens Society, American Medical Association, American Society of Cataract and Refractive Surgery, Contact Lens Association of Ophthalmologists, Medical Society of the State of New York, New York State Ophthalmological Society, Outpatient Ophthalmic Surgery Society

Disclosure: Nothing to disclose.

Maria Elena De Shazer University of California at Los Angeles

Disclosure: Nothing to disclose.

Jerre Freeman, MD Founder, Chairman, Memphis Eye and Cataract Associates; Clinical Professor, Department of Ophthalmology, University of Tennessee Health Science Center College of Medicine

Jerre Freeman, MD is a member of the following medical societies: American Academy of Ophthalmology, American Medical Association, American Society of Cataract and Refractive Surgery, and Tennessee Medical Association

Disclosure: Nothing to disclose.

Simon K Law, MD, PharmD Associate Professor of Ophthalmology, Jules Stein Eye Institute, University of California, Los Angeles, David Geffen School of Medicine

Simon K Law, MD, PharmD is a member of the following medical societies: American Academy of Ophthalmology, American Glaucoma Society, and Association for Research in Vision and Ophthalmology

Disclosure: Nothing to disclose.

Christopher J Rapuano, MD Professor, Department of Ophthalmology, Jefferson Medical College of Thomas Jefferson University; Director of the Cornea Service, Co-Director of Refractive Surgery Department, Wills Eye Institute

Christopher J Rapuano, MD is a member of the following medical societies: American Academy of Ophthalmology, American Society of Cataract and Refractive Surgery, Contact Lens Association of Ophthalmologists, Cornea Society, Eye Bank Association of America, International Society of Refractive Surgery, and Pan-American Association of Ophthalmology

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