G6PD Deficiency Questions & Answers

Updated: Apr 02, 2020
  • Author: Lawrence C Wolfe, MD; Chief Editor: George T Griffing, MD  more...
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Questions & Answers

Overview

What is glucose-6-phosphate dehydrogenase (G6PD) deficiency?

Which semi-quantitative tests are performed in the workup of glucose-6-phosphate dehydrogenase (G6PD) deficiency?

How is G6PD activity assessed in workup of glucose-6-phosphate dehydrogenase (G6PD) deficiency?

How is glucose-6-phosphate dehydrogenase (G6PD) deficiency treated?

What is the pathophysiology of glucose-6-phosphate dehydrogenase (G6PD) deficiency?

What is the prevalence of glucose-6-phosphate dehydrogenase (G6PD) deficiency?

What is the global prevalence of glucose-6-phosphate dehydrogenase (G6PD) deficiency?

Which patient groups have the highest prevalence of glucose-6-phosphate dehydrogenase (G6PD) deficiency?

What is the prognosis of glucose-6-phosphate dehydrogenase (G6PD) deficiency?

What is included in patient education about glucose-6-phosphate dehydrogenase (G6PD) deficiency?

Presentation

Which clinical history findings suggest glucose-6-phosphate dehydrogenase (G6PD) deficiency?

What are the signs and symptoms of glucose-6-phosphate dehydrogenase (G6PD) deficiency in neonates?

What are the signs and symptoms of acute hemolytic anemia in patients with glucose-6-phosphate dehydrogenase (G6PD) deficiency?

What are the signs and symptoms of chronic nonspherocytic hemolytic anemia (CNSHA) in patients with glucose-6-phosphate dehydrogenase (G6PD) deficiency?

Which physical findings are characteristic of glucose-6-phosphate dehydrogenase (G6PD) deficiency?

What causes glucose-6-phosphate dehydrogenase (G6PD) deficiency?

What are the variants of glucose-6-phosphate dehydrogenase (G6PD) deficiency?

How does the WHO classify the variants of glucose-6-phosphate dehydrogenase (G6PD) deficiency?

DDX

What are the differential diagnoses for G6PD Deficiency?

Workup

What are indications for testing for glucose-6-phosphate dehydrogenase (G6PD) deficiency?

What is the role of lab testing in the diagnosis of glucose-6-phosphate dehydrogenase (G6PD) deficiency?

Which semi-quantitative tests are performed in the workup of glucose-6-phosphate dehydrogenase (G6PD) deficiency?

What is the role of spectrophotometric assays in the workup of glucose-6-phosphate dehydrogenase (G6PD) deficiency?

What are the indications for glucose-6-phosphate dehydrogenase (G6PD) deficiency screening, and what are the guidelines for laboratory testing from the British Society for Haematology?

What is the role of imaging studies in the workup of glucose-6-phosphate dehydrogenase (G6PD) deficiency?

What is the role of genetic testing in the workup of glucose-6-phosphate dehydrogenase (G6PD) deficiency?

Treatment

How is glucose-6-phosphate dehydrogenase (G6PD) deficiency treated?

How is glucose-6-phosphate dehydrogenase (G6PD) deficiency treated in neonates?

How is anemia treated in glucose-6-phosphate dehydrogenase (G6PD) deficiency?

What is the role of vaccination in the treatment of glucose-6-phosphate dehydrogenase (G6PD) deficiency?

What are potential future treatments for glucose-6-phosphate dehydrogenase (G6PD) deficiency?

What is the role of surgery in the treatment of glucose-6-phosphate dehydrogenase (G6PD) deficiency?

Which specialist consultations are beneficial to patients with glucose-6-phosphate dehydrogenase (G6PD) deficiency?