Medication Summary

The goals of pharmacotherapy are to reduce morbidity and to prevent complications.

Class Summary

Indicated for recalcitrant conjunctival papilloma.

Cimetidine (Tagamet)

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May enhance immune system by inhibiting suppressor T-cell function and augmenting delayed-type hypersensitivity responses.

Class Summary

May induce delayed hypersensitivity reaction causing the tumor to regress. Exact mechanism is unknown.

Dinitrochlorobenzene

Contact sensitizers that induce allergic contact dermatitis, causing a localized inflammation and immune response.

Class Summary

Naturally produced proteins with antiviral, antitumor, and immunomodulatory actions.

Interferon alpha-2b (Intron A)

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Protein product manufactured by recombinant DNA technology. Mechanism of antitumor activity is not clearly understood; however, direct antiproliferative effects against malignant cells and modulation of host immune response may play important roles.

Class Summary

Inhibit cell growth and proliferation.

Mitomycin-C (Mutamycin)

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Acts like alkylating agent, inducing DNA cross-linking, primarily with guanine and cytosine base pairs, which, in turn, inhibits DNA synthesis.

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Author

Hon-Vu Quang Duong, MD Clinical Instructor of Ophthalmology and Ophthalmic Pathology, Westfield Eye Center; Senior Lecturer of Neurosciences (Anatomy and Physiology), Nevada State College

Hon-Vu Quang Duong, MD is a member of the following medical societies: American Academy of Ophthalmology

Disclosure: Nothing to disclose.

Specialty Editor Board

Francisco Talavera, PharmD, PhD Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Received salary from Medscape for employment. for: Medscape.

Christopher J Rapuano, MD Professor, Department of Ophthalmology, Sidney Kimmel Medical College of Thomas Jefferson University; Director of the Cornea Service, Wills Eye Hospital

Christopher J Rapuano, MD is a member of the following medical societies: American Academy of Ophthalmology, American Ophthalmological Society, American Society of Cataract and Refractive Surgery, Contact Lens Association of Ophthalmologists, Cornea Society, Eye Bank Association of America, International Society of Refractive Surgery

Disclosure: Serve(d) as a director, officer, partner, employee, advisor, consultant or trustee for: AAO; OMIC; American Society of Ophthalmic Trauma (ASOT); Avellino, Baxis; Bio-Tissue; Celularity; Dompe; Emmecell; Glaukos; Kala; Oyster Point; Sun Ophthalmics; Tarsus; TearLab<br/>Serve(d) as a speaker or a member of a speakers bureau for: Glaukos; Dompe; Bio-Tissue<br/>Received research grant from: Glaukos<br/>Received income in an amount equal to or greater than $250 from: AAO; OMIC; Baxis; Bio-Tissue; Cellularity; Dompe; Glaukos; Kala; Sun Ophthalmics; TearLab<br/>stock options for: RPS, Fount Bio.

Chief Editor

Hampton Roy, Sr, MD † Associate Clinical Professor, Department of Ophthalmology, University of Arkansas for Medical Sciences

Hampton Roy, Sr, MD is a member of the following medical societies: American Academy of Ophthalmology, American College of Surgeons, Pan-American Association of Ophthalmology

Disclosure: Nothing to disclose.

Additional Contributors

Robert A Copeland, Jr, MD † Chair, Professor, Department of Ophthalmology, Howard University College of Medicine

Robert A Copeland, Jr, MD is a member of the following medical societies: American Academy of Ophthalmology

Disclosure: Nothing to disclose.

Stephen D Plager, MD

Stephen D Plager, MD is a member of the following medical societies: American College of Surgeons, American Medical Association, American Society of Cataract and Refractive Surgery, California Medical Association

Disclosure: Nothing to disclose.

Sections Conjunctival Papilloma
Overview
Presentation
- History
- Physical
- Causes
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DDx
Workup
Treatment
Medication
References

Conjunctival Papilloma Medication

Medication Summary

H2-receptor antagonists