Granular Corneal Dystrophy Medication

Updated: May 02, 2018
  • Author: Jean Deschênes, MD, FRCSC; Chief Editor: Hampton Roy, Sr, MD  more...
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Medication Summary

Medical therapy for recurrent corneal erosions includes hypertonic saline, which is believed to increase adherence of epithelium to the underlying stroma. Lubrication, especially at bedtime, also may help prevent further corneal erosions.


Hypertonic saline drops

Class Summary

This agent dehydrates the epithelium, allowing it to better adhere to underlying stroma.

Sodium chloride hypertonic, ophthalmic (Adsorbonac, Afrin Saline Mist, Muro 128)

Used for temporary relief of corneal edema.


Lubricating agents

Class Summary

These agents can moisten ocular surface and decrease the frequency of recurrent erosions.

Artificial tears (Celluvisc, Murine, Refresh, GenTeal, Refresh PM, Lacri-Lube)

Contains equivalent of 0.9% NaCl and are used to maintain ocular tonicity. Acts to stabilize and thicken precorneal tear film and prolong tear film breakup time, which occurs with dry eye states.