Map-dot-fingerprint Dystrophy Workup

Updated: Feb 14, 2019
  • Author: David D Verdier, MD; Chief Editor: Hampton Roy, Sr, MD  more...
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Histologic Findings

The corneal maps in map-dot-fingerprint dystrophy histologically represent areas of multilaminar basement membrane, which extend into the epithelium. The corneal dots in map-dot-fingerprint dystrophy are intraepithelial microcysts that contain nuclear, cytoplasmic, and lipid debris. The corneal fingerprints in map-dot-fingerprint dystrophy are curvilinear clusters of reduplicated and thickened basement membrane and fibrillogranular material. [17, 12]

Blebs, a less common manifestation of map-dot-fingerprint dystrophy, are localized areas of fibrillogranular material or thickened basement membrane.