Neovascularization, Corneal, CL-related Workup

Updated: Apr 18, 2018
  • Author: Barry A Weissman, OD, PhD, FAAO; Chief Editor: Hampton Roy, Sr, MD  more...
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Laboratory Studies

For systemic medical reasons, it is important to obtain a thorough case history of CL wear and to exclude other potential causes of corneal NV, especially if NV is seen deep in the corneal stroma. Pay attention to causes of interstitial keratitis such as herpes keratitis, tuberculosis, measles, and syphilis.

Laboratory studies may include the following:

  • Herpes cultures if herpes is suspected and the diagnosis cannot be made on clinical examination
  • Tuberculosis (TB) skin test and/or chest radiography if TB is suspected
  • Rapid plasma reagin (RPR) and microhemagglutination- Treponema pallidum (MHA-TP) if syphilis is suspected