Peripheral Ulcerative Keratitis Questions & Answers

Updated: Jun 11, 2019
  • Author: Ellen N Yu-Keh, MD; Chief Editor: Andrew A Dahl, MD, FACS  more...
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Questions & Answers

Overview

What is peripheral ulcerative keratitis (PUK)?

What is the pathophysiology of peripheral ulcerative keratitis (PUK)?

What is the prevalence of peripheral ulcerative keratitis (PUK) in the US?

What is the morbidity associated with peripheral ulcerative keratitis (PUK)?

What are the racial predilections of peripheral ulcerative keratitis (PUK)?

What are the sexual predilections of peripheral ulcerative keratitis (PUK)?

Which age groups have the highest prevalence of peripheral ulcerative keratitis (PUK)?

Presentation

Which clinical history findings are characteristic of peripheral ulcerative keratitis (PUK)?

What are the symptoms of underlying systemic disease in peripheral ulcerative keratitis (PUK)?

Which physical findings are characteristic of peripheral ulcerative keratitis (PUK)?

What causes peripheral ulcerative keratitis (PUK)?

Which conditions are included in the differential diagnoses of peripheral ulcerative keratitis (PUK)?

DDX

What are the differential diagnoses for Peripheral Ulcerative Keratitis?

Workup

What is the role of lab tests in the workup of peripheral ulcerative keratitis (PUK)?

What is the role of imaging studies in the workup of peripheral ulcerative keratitis (PUK)?

What is the role of biopsy in the workup of peripheral ulcerative keratitis (PUK)?

Which histologic findings are characteristic of peripheral ulcerative keratitis (PUK)?

Treatment

How is peripheral ulcerative keratitis (PUK) treated?

What is the role of immunosuppressive drugs in the treatment of peripheral ulcerative keratitis (PUK)?

What is the role of cyclophosphamide in the treatment of peripheral ulcerative keratitis (PUK)?

What is the role of infliximab in the treatment of peripheral ulcerative keratitis (PUK)?

What is the role of rituximab in the treatment of peripheral ulcerative keratitis (PUK)?

What is the role of surgery in the treatment of peripheral ulcerative keratitis (PUK)?

Which specialist consultations are beneficial to patients with peripheral ulcerative keratitis (PUK)?

Medications

What are the goals of drug treatment for peripheral ulcerative keratitis (PUK)?

Which medications in the drug class Disease modifying agents are used in the treatment of Peripheral Ulcerative Keratitis?

Which medications in the drug class Immunosuppressant agents are used in the treatment of Peripheral Ulcerative Keratitis?

Which medications in the drug class Systemic corticosteroids are used in the treatment of Peripheral Ulcerative Keratitis?

Follow-up

What is included in the long-term monitoring of peripheral ulcerative keratitis (PUK)?

What are the possible complications of peripheral ulcerative keratitis (PUK)?

What is the prognosis of peripheral ulcerative keratitis (PUK)?

What is included in patient education about peripheral ulcerative keratitis (PUK)?