Infantile Esotropia Medication

Updated: May 20, 2021
  • Author: Vicente Victor Dizon Ocampo, Jr, MD; Chief Editor: Donny W Suh, MD, MBA, FAAP, FACS  more...
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Medication

Medication Summary

Very few medications are used in the treatment of infantile esotropia. Combination antibiotic-steroid ointments are prescribed for the first postoperative week. BOTOX® injection has been used as an alternative to initial or repeat surgical ocular alignment.

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Combination antibiotic-steroid ointments

Class Summary

Used in first postoperative week to control any inflammation and to prevent any infection resulting from surgery, particularly in the conjunctiva.

Dexamethasone/tobramycin (TobraDex)

Consist of 0.3% tobramycin and 0.1% dexamethasone. Tobramycin has been found to be active against numerous gram-positive (eg, Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pneumoniae) and gram-negative organisms (eg, Pseudomonas aeruginosa). Dexamethasone is a potent corticoid.

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Neurotoxins

Class Summary

Botulinum toxin type A (BOTOX®) is most commonly used. Inhibits transmission of nerve impulses in neuromuscular tissue.

OnabotulinumtoxinA (BOTOX®)

Blocks neuromuscular conduction by binding to receptor sites on motor nerve terminals, entering nerve terminals, and inhibiting the release of acetylcholine. Intended for injection into extraocular muscles. Initial doses administered in 1.25-2.5 U. Use lower doses for smaller deviations and larger doses for larger deviations.

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