Postoperative Endophthalmitis Medication

Updated: Jan 15, 2019
  • Author: Hemang K Pandya, MD, FACS; Chief Editor: Hampton Roy, Sr, MD  more...
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Medication

Medication Summary

These drugs are recommended for the treatment of acute postoperative endophthalmitis after cataract extraction.

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Antibiotics, Other

Class Summary

Therapy must be comprehensive and cover all likely pathogens in the context of this clinical setting.

Vancomycin (Vancocin)

Indicated for treatment of serious or severe infections caused by gram-positive organisms.

Ceftazidime (Fortaz, Tazicef)

Third-generation cephalosporin with broad-spectrum, gram-negative activity; lower efficacy against gram-positive organisms; higher efficacy against resistant organisms. Arrests bacterial growth by binding to one or more penicillin-binding proteins.

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Corticosteroids

Class Summary

Have anti-inflammatory properties and cause profound and varied metabolic effects. Corticosteroids modify the body's immune response to diverse stimuli.

Dexamethasone (Baycadron)

Decreases inflammation by suppressing migration of polymorphonuclear leukocytes and reducing capillary permeability.

Prednisolone ophthalmic (Omnipred, Pred Forte, Pred Mild)

Synthetic analog of naturally occurring glucocorticoid used to suppress the inflammatory response.

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