Imaging Studies

Digital infrared iris photography may yield informative image patterns.^[37]

Procedures

Perform gonioscopy to rule out closed-angle glaucoma.

Consider anterior chamber paracentesis and aqueous sampling to evaluate for CMV infection.

Histologic Findings

Microscopic examination of trabeculectomy specimens taken at the time of an acute attack reveals inflammation with an abundant mononuclear cell infiltration of the trabecular meshwork.

KPs seen in the setting on CMV endotheliitis are often medium-sized and coin-shaped lesions. On confocal microscopy of these lesions, the classic “owl eye cells” named for large endothelial cells containing nuclei of high reflection surrounded by a halo of low reflection are visible.^[38]

Treatment & Management

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Author

Leonard K Seibold, MD Assistant Professor, Co-Director, Glaucoma Fellowship, Department of Ophthalmology, University of Colorado School of Medicine

Leonard K Seibold, MD is a member of the following medical societies: American Academy of Ophthalmology, American Glaucoma Society, Association for Research in Vision and Ophthalmology, Chandler Grant Glaucoma Society, Colorado Society of Eye Physicians and Surgeons

Disclosure: Nothing to disclose.

Coauthor(s)

Erin G Sieck, MD Resident Physician, Department of Ophthalmology, University of Colorado School of Medicine

Erin G Sieck, MD is a member of the following medical societies: American Academy of Ophthalmology

Disclosure: Nothing to disclose.

Specialty Editor Board

Francisco Talavera, PharmD, PhD Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Received salary from Medscape for employment. for: Medscape.

Martin B Wax, MD Professor, Department of Ophthalmology, University of Texas Southwestern Medical School; Vice President, Research and Development, Head, Ophthalmology Discovery Research and Preclinical Sciences, Alcon Laboratories, Inc

Martin B Wax, MD is a member of the following medical societies: American Academy of Ophthalmology, American Glaucoma Society, Society for Neuroscience

Disclosure: Nothing to disclose.

Chief Editor

Hampton Roy, Sr, MD † Associate Clinical Professor, Department of Ophthalmology, University of Arkansas for Medical Sciences

Hampton Roy, Sr, MD is a member of the following medical societies: American Academy of Ophthalmology, American College of Surgeons, Pan-American Association of Ophthalmology

Disclosure: Nothing to disclose.

Additional Contributors

Andrew I Rabinowitz, MD Director of Glaucoma Service, Barnet Dulaney Perkins Eye Center

Andrew I Rabinowitz, MD is a member of the following medical societies: Aerospace Medical Association, American Academy of Ophthalmology, American Society for Laser Medicine and Surgery, American Academy of Ophthalmology, American Medical Association

Disclosure: Nothing to disclose.

James H Oakman, Jr, MD Partner, Southern Eye Center, Augusta, Georgia

James H Oakman, Jr, MD is a member of the following medical societies: Association of American Physicians and Surgeons, Georgia Medical Society, Georgia Society of Ophthalmology, Georgia Society of the American College of Surgeons, American Academy of Ophthalmology, American Society of Cataract and Refractive Surgery

Disclosure: Nothing to disclose.