Dacryocystitis Medication

Updated: Jul 20, 2018
  • Author: Grant D Gilliland, MD; Chief Editor: Edsel Ing, MD, MPH, FRCSC  more...
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Medication

Medication Summary

Oral and topical antibiotics are the mainstay of medical therapy. [15]

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Antibiotics

Class Summary

Used to treat systemic infections, including periorbital cellulitis, orbital cellulitis, and sinusitis.

Amoxicillin and clavulanate (Augmentin)

Provides useful coverage for most organisms associated with dacryocystitis.

Ampicillin and sulbactam (Unasyn)

Provides useful coverage for most organisms associated with dacryocystitis.

Levofloxacin (Levaquin)

Provides useful coverage for most organisms associated with dacryocystitis.

Trimethoprim/polymyxin B ophthalmic (Polytrim Ophthalmic Solution)

For ocular infections, involving cornea or conjunctiva, resulting from strains of microorganisms susceptible to this antibiotic. Available as a solution and ointment.

Gentamicin (Genoptic, Ocumycin)

Aminoglycoside antibiotic used for gram-negative bacterial coverage.

Tobramycin ophthalmic (AKTob, Tobrex)

Interferes with bacterial protein synthesis by binding to 30S and 50S ribosomal subunits, which results in a defective bacterial cell membrane.

Dexamethasone/tobramycin (TobraDex ST, TobraDex)

Tobramycin interferes with bacterial protein synthesis by binding to 30S and 50S ribosomal subunits, which results in a defective bacterial cell membrane. Dexamethasone decreases inflammation by suppressing migration of polymorphonuclear leukocytes and reducing capillary permeability.

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