Entropion Medication

Updated: May 24, 2019
  • Author: Christopher DeBacker, MD; Chief Editor: Hampton Roy, Sr, MD  more...
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Medication

Medication Summary

Topical, local, and systemic medications may be useful in the management of various forms of entropion.

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Ocular lubricants

Class Summary

Topical ocular lubricants may be necessary to increase patient comfort and to diminish abrasive conjunctivopathy and keratopathy.

Artificial tears

Preservative-free artificial tears are preferred to avoid preservative-associated ocular reactions.

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Immunosuppressive agents

Class Summary

These medications have been shown to effectively diminish the autoinflammatory reaction associated with ocular cicatricial pemphigoid.

Dapsone (Avlosulfon)

Bactericidal and bacteriostatic against mycobacteria; mechanism of action is similar to that of sulfonamides where competitive antagonists of PABA prevent formation of folic acid, inhibiting bacterial growth.

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Neuromuscular transmission blocking agents

Class Summary

Weakening or paralyzing the orbicularis muscle of the lower eyelid helps in preventing the inturning of the lower eyelid in cases of spastic and involutional entropion.

OnabotulinumtoxinA (BOTOX®)

Temporarily paralyzes the muscles by inhibiting acetylcholine release. Duration of effectiveness usually is 3-4 mo.

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