Amblyopia Medication

Updated: Apr 05, 2016
  • Author: Kimberly G Yen, MD; Chief Editor: Hampton Roy, Sr, MD  more...
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Medication

Medication Summary

Pharmacologic treatment with levodopa has been investigated and has showed transient improvement of vision in amblyopic eyes. However, the exact role of such pharmacologic agents has not been determined. The Pediatric Eye Disease Investigator Group demonstrated that levodopa is not as effective as an adjunctive treatment in amblyopia. Levodopa currently is not being used clinically. [30]

Atropine penalization (with either ointment or drops) is an alternative method of blurring vision in the sound eye of patients who refuse patching. It may be applied once a day to patients in the preferred eye only.

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Cycloplegics

Class Summary

These agents are used to blur vision in one eye to treat amblyopia in the contralateral eye.

Atropine ophthalmic (Isopto, Atropair, Atropisol)

A topically applied muscarinic antagonist, which blocks the action of acetylcholine. This results in paralysis of the iris sphincter and resultant pupillary dilation. Paralysis of the ciliary muscles also occurs, which inhibits accommodation and relieves pain in iridocyclitis. The medication is dispensed in a topical formulation, either an ointment or a solution.

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