Exophthalmos (Proptosis) Medication

Updated: Sep 25, 2018
  • Author: Michael Mercandetti, MD, MBA, FACS; Chief Editor: Hampton Roy, Sr, MD  more...
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Medication Summary

The goals of pharmacotherapy are to reduce morbidity and to prevent complications.


Lubricants, Ophthalmic

Class Summary

Lubricants act as humectants in the eye. The ideal artificial lubricant should be preservative-free  and have a polymeric system to increase its retention time. Lubricating drops are used to reduce morbidity and to prevent complications. Lubricating ointments prevent complications from dry eyes.

Artificial tears (Celluvisc, Murine, Refresh, Tears Naturale)

Contains equivalent of 0.9% NaCl and maintains ocular tonicity. Acts to stabilize and thicken precorneal tear film and prolongs tear film breakup time, which occurs with dry eye states.

Polyethylene glycol 400/propylene glycol ophthalmic (Systane Balance, Systane Ultra, Tears Naturale Free, Hypo Tears, Murine Tears)

These substances serve as lubricants.

Carboxymethylcellulose ophthalmic (Refresh Optive Gel Drops, TheraTears Nighttime Dry Eye Therapy)

Carboxymethylcellulose is used to protect and lubricate mucous membranes surfaces and relieve dryness and irritation.

Hypromellose/carboxymethylcellulose ophthalmic (Genteal Lubricant Eye Drops, Moderate-to-Severe)

Increases lubrication of the eye, which in turn prevents complications and reduces morbidity.