Enophthalmos Differential Diagnoses

Updated: Sep 20, 2018
  • Author: Charles NS Soparkar, MD, PhD; Chief Editor: Hampton Roy, Sr, MD  more...
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Differential Diagnoses

  • Congenital enophthalmos

    Soft-tissue intraorbital deficiency, such as microphthalmos or anophthalmos

    Bone growth problems

  • Orbital cavity expansion

    Orbital bone out-fracture

    Surgical expansion, ie, orbital decompression

    Silent sinus syndrome

    Orbital varix

    Granulomatous, bone necrosing disorders

  • Pseudoenophthalmos

    Ipsilateral upper eyelid ptosis and/or lower eyelid reverse ptosis

    Superior sulcus volume loss or elevated eyelid crease

    Horner syndrome

  • Pseudoenophthalmos due to contralateral exophthalmos


    Orbital bone in-fracture, such as ZMC fractures

    Thyroid ophthalmopathy

  • Pseudoenophthlamos due to contralateral pseudoexophthalmos

    High myopia



    Eyelid retraction

    Lagophthalmos (ie, Bell palsy)

  • Volumetric loss of orbital soft tissue contents

    Orbital fat atrophy

    Orbital fat sclerosis and contraction

    Following orbital tumor resection

    Small or shrinking eye