Capillary Hemangioma Medication

Updated: Oct 06, 2015
  • Author: Stuart Seiff, MD, FACS; Chief Editor: Hampton Roy, Sr, MD  more...
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Medication

Medication Summary

The goals of pharmacotherapy are to reduce morbidity and to prevent complications.

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Corticosteroids

Class Summary

Have anti-inflammatory properties and cause profound and varied metabolic effects. Corticosteroids modify the body's immune response to diverse stimuli.

Prednisone (Deltasone)

Decreases inflammation by stabilizing lysosomal membranes, inhibiting PMN and mast cell degranulation, and decreasing capillary vasoconstriction.

Clobetasol propionate 0.05% (Temovate)

Decreases inflammation by stabilizing lysosomal membranes, inhibiting PMN and mast cell degranulation. Class I superpotent topical steroid; suppresses mitosis and increases synthesis of proteins that decrease inflammation and cause vasoconstriction.

Betamethasone (Celestone)

Decreases inflammation by suppressing migration of polymorphonuclear leukocytes and reversing increased capillary permeability.

Triamcinolone (Kenalog)

Treats inflammatory dermatosis that is responsive to steroids. Decreases inflammation by suppressing the migration of polymorphonuclear leukocytes and reversing capillary permeability.

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Beta-adrenergic Blocker

Class Summary

The adrenergic system is the major regulator of cardiac and vascular function.

Propranolol (Inderal)

Nonselective beta-adrenergic blocker. Its mechanism of action in shrinking hemangiomas remains unknown. Beta-2 adrenergic receptors are present on endothelial cells of hemangiomas.

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