Low LDL Cholesterol (Hypobetalipoproteinemia) Medication

Updated: Aug 19, 2021
  • Author: Vibhuti N Singh, MD, MPH, FACC, FSCAI; Chief Editor: George T Griffing, MD  more...
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Medication Summary

Abetalipoproteinemia (ABL) and familial hypobetalipoproteinemia (FHBL) have no specific medical therapy other than vitamin supplementation, particularly high doses of vitamin E. Symptomatic medications for diarrhea and treatment of the cause of malabsorption may be needed. Dietary treatment related to ABL and FHBL is quite rigorous.



Class Summary

High-dose vitamin E therapy is used to raise tissue levels of tocopherol and to prevent the development of neurologic sequelae.

Vitamin E (Vita-Plus E Softgels, Vitec, Aquasol E)

Vitamin E protects polyunsaturated fatty acids in membranes from attack by free radicals and protects red blood cells against hemolysis.

Vitamin A (Del-Vi-A, Palmitate-A 5000)

Cofactor in many biochemical processes.