Hypoglycemia Questions & Answers

1. Mathew P, Thoppil D. Hypoglycemia. 2018 Jan. [QxMD MEDLINE Link]. [Full Text].

2. Pugh SK, Doherty DA, Magann EF, et al. Does hypoglycemia following a glucose challenge test identify a high risk pregnancy?. Reprod Health. 2009 Jul 14. 6:10. [QxMD MEDLINE Link]. [Full Text].

3. Zhong VW, Juhaeri J, Cole SR, et al. Proximal HbA1C Level and First Hypoglycemia Hospitalization in Adults with Incident Type 2 Diabetes. J Clin Endocrinol Metab. 2019 Jan 3. [QxMD MEDLINE Link].

4. Riegger LQ, Leis AM, Golmirzaie KH, Malviya S. Risk Factors for Intraoperative Hypoglycemia in Children: A Multicenter Retrospective Cohort Study. Anesth Analg. 2020 Jun 25. [QxMD MEDLINE Link].

5. van Furth AM, de Heide LJM, Emous M, Veeger N, van Beek AP. Dumping Syndrome and Postbariatric Hypoglycemia: Supporting Evidence for a Common Etiology. Surg Obes Relat Dis. 2021 May 19. [QxMD MEDLINE Link]. [Full Text].

6. Hughes S. Pain Med Linked to Hypoglycemia. Medscape Medical News. Dec 11 2014. [Full Text].

7. Fournier JP, Azoulay L, Yin H, et al. Tramadol Use and the Risk of Hospitalization for Hypoglycemia in Patients With Noncancer Pain. JAMA Intern Med. 2014 Dec 8. [QxMD MEDLINE Link].

8. Eriksson JW, Bodegard J, Nathanson D, Thuresson M, Nystrom T, Norhammar A. Sulphonylurea compared to DPP-4 inhibitors in combination with metformin carries increased risk of severe hypoglycemia, cardiovascular events, and all-cause mortality. Diabetes Res Clin Pract. 2016 Jul. 117:39-47. [QxMD MEDLINE Link].

9. Gautier JF, Monguillon P, Verier-Mine O, et al. Which oral antidiabetic drug to combine with metformin to minimize the risk of hypoglycemia when initiating basal insulin?: A randomized controlled trial of a DPP4 inhibitor versus insulin secretagogues. Diabetes Res Clin Pract. 2016 Jun. 116:26-8. [QxMD MEDLINE Link].

10. Awad DH, Gokarakonda SB, Ilahi M. Factitious Hypoglycemia. StatPearls. 2021 Jan. [QxMD MEDLINE Link]. [Full Text].

11. Lamounier RN, Geloneze B, Leite SO, et al. Hypoglycemia incidence and awareness among insulin-treated patients with diabetes: the HAT study in Brazil. Diabetol Metab Syndr. 2018. 10:83. [QxMD MEDLINE Link]. [Full Text].

12. Hill NR, Thompson B, Bruce J, et al. Glycaemic risk assessment in children and young people with Type 1 diabetes mellitus. Diabet Med. 2009 Jul. 26(7):740-3. [QxMD MEDLINE Link].

13. Turnbull FM, Abraira C, Anderson RJ, et al. Intensive glucose control and macrovascular outcomes in type 2 diabetes. Diabetologia. 2009 Aug 5. [QxMD MEDLINE Link].

14. Prolonged Nocturnal Hypoglycemia Is Common During 12 Months Of Continuous Glucose Monitoring In Children And Adults With Type 1 Diabetes. Diabetes Care. 2010 Mar 3. [QxMD MEDLINE Link]. [Full Text].

15. Swinnen SG, Dain MP, Aronson R, et al. A 24-week, randomized, treat-to-target trial comparing initiation of insulin glargine once-daily with insulin detemir twice-daily in patients with type 2 diabetes inadequately controlled on oral glucose-lowering drugs. Diabetes Care. 2010 Mar 3. [QxMD MEDLINE Link].

16. Ito T, Otsuki M, Igarashi H, et al. Epidemiological Study of Pancreatic Diabetes in Japan in 2005: A Nationwide Study. Pancreas. 2010 Feb 22. [QxMD MEDLINE Link].

17. Chen L. A literature review of intensive insulin therapy and mortality in critically ill patients. Clin Nurse Spec. 2010 Mar-Apr. 24(2):80-6. [QxMD MEDLINE Link].

18. Garza H. Minimizing the risk of hypoglycemia in older adults: a focus on long-term care. Consult Pharm. 2009 Jun. 24 Suppl B:18-24. [QxMD MEDLINE Link].

19. Boucai L, Southern WN, Zonszein J. Hypoglycemia-associated Mortality Is Not Drug-associated but Linked to Comorbidities. Am J Med. 2011 Nov. 124(11):1028-35. [QxMD MEDLINE Link]. [Full Text].

20. Feil DG, Rajan M, Soroka O, et al. Risk of hypoglycemia in older veterans with dementia and cognitive impairment: implications for practice and policy. J Am Geriatr Soc. 2011 Dec. 59(12):2263-72. [QxMD MEDLINE Link].

21. Parikh NS, Ahlawat R. Glycogen Storage Disease Type I (Von Gierke Disease). 2018 Jan. [QxMD MEDLINE Link]. [Full Text].

22. Lin YY, Hsu CW, Sheu WH, Chu SJ, Wu CP, Tsai SH. Use of therapeutic responses to glucose replacement to predict glucose patterns in diabetic patients presenting with severe hypoglycaemia. Int J Clin Pract. 2009 Aug. 63(8):1161-6. [QxMD MEDLINE Link].

23. Craig CM, McLaughlin TL. Defining clinically important hypoglycemia in patients with postbariatric hypoglycemia. Surg Obes Relat Dis. 2021 Jun 29. [QxMD MEDLINE Link].

24. Middleton TL, Wong J, Molyneaux L, et al. Cardiac Effects of Sulfonylurea-Related Hypoglycemia. Diabetes Care. 2017 Feb 21. [QxMD MEDLINE Link].

25. Mezquita-Raya P, Reyes-Garcia R, de Torres-Sanchez A, Matarin MG, Cepero-Garcia D, Perez de Isla L. Electrical changes during hypoglycaemia in patients with type 1 and type 2 diabetes and high cardiovascular risk. Diabetes Res Clin Pract. 2018 Jan 31. 138:44-6. [QxMD MEDLINE Link].

26. Egi M, Bellomo R, Stachowski E, et al. Hypoglycemia and outcome in critically ill patients. Mayo Clin Proc. 2010 Mar. 85(3):217-24. [QxMD MEDLINE Link]. [Full Text].

27. Ohashi Y, Wolden ML, Hyllested-Winge J, Brod M. The diabetes management and daily functioning burden of non-severe hypoglycaemia in Japanese people treated with insulin. J Diabetes Investig. 2017 Feb 8. [QxMD MEDLINE Link]. [Full Text].

28. New Guidelines Stress Hypoglycemia Affects All Diabetics. Medscape Medical News. Available at http://www.medscape.com/viewarticle/802949?nlid=30763_1621. Accessed: May 2, 2013.

29. Seaquist ER, Anderson J, Childs B, Cryer P, Dagogo-Jack S, Fish L, et al. Hypoglycemia and diabetes: a report of a workgroup of the american diabetes association and the endocrine society. Diabetes Care. 2013 May. 36(5):1384-95. [QxMD MEDLINE Link]. [Full Text].

30. Kong AP, Chan JC. Hypoglycemia and Comorbidities in Type 2 Diabetes. Curr Diab Rep. 2015 Oct. 15 (10):646. [QxMD MEDLINE Link].

Osama Hamdy, MD, PhD Medical Director, Obesity Clinical Program, Director of Inpatient Diabetes Program, Joslin Diabetes Center; Associate Professor of Medicine, Harvard Medical School

Osama Hamdy, MD, PhD is a member of the following medical societies: American Association of Clinical Endocrinologists, American Diabetes Association

Disclosure: Serve(d) as a director, officer, partner, employee, advisor, consultant or trustee for: on advisory panel of Astra-Zeneca Inc<br/>Received research grant from: USDA Dairy Council <br/>Have a 5% or greater equity interest in: HealthyMation Inc<br/>Received consulting fee from Merck Inc for teaching; Received consulting fee from Abbott Nutrition for consulting; for: Receieved consulting fee Sanofi Aventis for teaching.

Vellore A R Srinivasan, MSc, PhD Professor of Biochemistry, Mahatma Gandhi Medical College and Research Institute, Sri Balaji Vidyapeeth University, India

Disclosure: Received salary from Sri Balaji Vidyapeeth University, Mahatma Gandhi Medical College and Research Institute campus , Pondicherry ( Puducherry ) , India . P.C. 607 402 for employment.

Kenneth J Snow, MD Associate Chief, Adult Diabetes, Joslin Clinic

Kenneth J Snow, MD is a member of the following medical societies: American Association of Clinical Endocrinologists, American College of Endocrinology, American Diabetes Association, Endocrine Society

Disclosure: Nothing to disclose.

Romesh Khardori, MD, PhD, FACP (Retired) Professor, Division of Endocrinology, Diabetes and Metabolism, Department of Internal Medicine, Eastern Virginia Medical School

Romesh Khardori, MD, PhD, FACP is a member of the following medical societies: American Association of Clinical Endocrinologists, American College of Physicians, American Diabetes Association, Endocrine Society

Disclosure: Nothing to disclose.

Vasudevan A Raghavan, MBBS, MD, MRCP(UK) Director, Cardiometabolic and Lipid (CAMEL) Clinic Services, Division of Endocrinology, Scott and White Hospital, Texas A&M Health Science Center College of Medicine

Vasudevan A Raghavan, MBBS, MD, MRCP(UK) is a member of the following medical societies: American College of Physicians-American Society of Internal Medicine, American Diabetes Association, American Heart Association, Endocrine Society, National Lipid Association, and Royal College of Physicians

Disclosure: Nothing to disclose.

David S Schade, MD Chief, Division of Endocrinology and Metabolism, Professor, Department of Internal Medicine, University of New Mexico School of Medicine and Health Sciences Center

David S Schade, MD is a member of the following medical societies: American College of Physicians, American Diabetes Association, American Federation for Medical Research, Endocrine Society, New Mexico Medical Society, New York Academy of Sciences, and Society for Experimental Biology and Medicine

Disclosure: Nothing to disclose.

Francisco Talavera, PharmD, PhD Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Medscape Salary Employment

• Print this section
• Print the entire contents of
• Print the entire contents of article