Insulin Resistance Questions & Answers

Updated: Aug 07, 2019
  • Author: Samuel T Olatunbosun, MD, FACP, FACE; Chief Editor: George T Griffing, MD  more...
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Questions & Answers

Overview

What is insulin resistance?

What is the pathophysiology of insulin resistance?

What is the pathophysiology of metabolic syndrome?

What is the role of genetics in the etiology of insulin resistance?

What causes acquired insulin resistance?

How are the causes of insulin resistance classified?

Which specific conditions or agents may cause insulin resistance?

What is the prevalence of insulin resistance in the US?

What is the global prevalence of insulin resistance?

Which age groups have the highest prevalence of insulin resistance?

What are the sexual predilections of insulin resistance?

What are the racial predilections of insulin resistance?

What is the prognosis of insulin resistance?

What is included in patient education about insulin resistance?

Presentation

Which clinical history findings are characteristic of insulin resistance?

Which blood pressure findings are characteristic of insulin resistance?

How is obesity characterized in insulin resistance?

Which cardiovascular findings are characteristic of insulin resistance?

Which physical findings are characteristic of type A syndrome–caused insulin resistance?

Which physical findings are characteristic of acanthosis nigricans in patients with insulin resistance?

Which physical findings are characteristic of polycystic ovary syndrome (PCOS) in patients with insulin resistance?

Which physical findings are characteristic of type B syndrome caused insulin resistance?

Which physical findings are characteristic of insulin-resistant states?

What are the possible complications of insulin resistance?

DDX

What are the most commonly used diagnostic criteria for insulin resistance?

What are the NCEP/ATP III criteria for metabolic syndrome?

What are the WHO diagnostic criteria for metabolic syndrome?

What are the AACE clinical criteria for insulin resistance syndrome?

What are the differences between the NCEP/ATPIII, WHO, and AACE criteria for insulin resistance?

What are the IDF diagnostic criteria for metabolic syndrome?

What are the differential diagnoses for Insulin Resistance?

Workup

How is insulin resistance diagnosed?

What is the role of lab tests in the workup of insulin resistance?

How is insulin sensitivity assessed in the workup of insulin resistance?

How is cardiovascular risk assessed in the workup of insulin resistance?

Treatment

How is insulin resistance treated?

Which specialist consultations are beneficial to patients with insulin resistance?

Which medications are used in the treatment of insulin resistance?

What is the role of surgery in the treatment of insulin resistance?

Medications

What is the role of medications in the treatment of insulin resistance?

Which medications in the drug class Antidiabetics, Glucagon-like Peptide-1 Agonists are used in the treatment of Insulin Resistance?

Which medications in the drug class Lipase Inhibitors are used in the treatment of Insulin Resistance?

Which medications in the drug class Antidiabetic Agents, Insulin are used in the treatment of Insulin Resistance?

Which medications in the drug class Corticosteroids are used in the treatment of Insulin Resistance?

Which medications in the drug class Antidiabetic Agents, Thiazolidinediones are used in the treatment of Insulin Resistance?

Which medications in the drug class Antidiabetic Agents, Biguanides are used in the treatment of Insulin Resistance?