Hemoglobinopathy Retinopathy Medication

Updated: Aug 22, 2016
  • Author: Brian A Phillpotts, MD, MD; Chief Editor: Hampton Roy, Sr, MD  more...
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Medication

Medication Summary

See Special Concerns and Surgical Care.

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Hemostatic agents

Class Summary

Reduce the incidence of rebleeds in the setting of hyphema.

Aminocaproic acid (Amicar)

Inhibits fibrinolysis via inhibition of plasminogen activator substances; to a lesser degree, through antiplasmin activity.

Main problem is that the thrombi that form during treatment are not lysed, and effectiveness is uncertain.

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Corticosteroids

Class Summary

Reduce the incidence of rebleeds in the setting of hyphema.

Prednisolone 1% (Pred Forte)

Decreases inflammation by suppressing migration of polymorphonuclear leukocytes and reversing increased capillary permeability.

Prednisone (Deltasone, Orasone, Meticorten)

May decrease inflammation by reversing increased capillary permeability and suppressing PMN activity.

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