Best Disease Treatment & Management

Updated: Oct 10, 2016
  • Author: Michael Altaweel, MD, FRCSC; Chief Editor: Hampton Roy, Sr, MD  more...
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Treatment

Medical Care

No treatment exists for vitelliform macular dystrophy (Best disease). Secondary choroidal neovascularization can be managed with direct laser treatment or photodynamic therapy. [29, 30] More recently, treatment with anti–vascular endothelial growth factor (VEGF) therapy, including intravitreal injection of bevacizumab, has also been described. [5]

Evaluation of family members is important to identify carriers and individuals with vitelliform macular dystrophy. Both genetic counseling and career counseling are provided.

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Consultations

Consult a vitreoretinal disease specialist for the initial diagnosis, electrophysiology testing, and family assessment, as well as for the long-term follow-up care of patients to monitor disease progression and choroidal neovascularization.

Consult a low vision specialist who can provide specialized equipment to assist individuals who have significant deterioration in visual acuity in both eyes.

Occupational counseling is important. Although most patients retain reading vision in at least 1 eye throughout life, visual deterioration can occur, particularly beyond age 40 years. This knowledge may influence the choice of career.

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Diet

Diet is not known to influence the progression of Best disease.

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Activity

Physical activity does not influence the progression of Best disease.

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