Episcleritis Differential Diagnoses

Updated: Feb 04, 2022
  • Author: Ellen N Yu-Keh, MD; Chief Editor: Andrew A Dahl, MD, FACS  more...
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Diagnostic Considerations

Other conditions to consider when episcleritis is suspected include malignancy and scleritis.


Episcleritis has been reported to be the presenting sign of conjunctival lymphoma. [6]


It is important to differentiate episcleritis from scleritis because they differ in terms of prognosis and their association with systemic diseases.

Scleritis, which is much less common than episcleritis, is more commonly associated with connective tissue or vasculitic diseases than is episcleritis. Moreover, ocular complications such as decreased vision, anterior uveitis, peripheral ulcerative keratitis, and ocular hypertension are more commonly seen in scleritis than in episcleritis.

Differential Diagnoses