Myxedema Coma or Crisis Questions & Answers

Updated: Mar 27, 2017
  • Author: Mohsen S Eledrisi, MD, FACP, FACE; Chief Editor: George T Griffing, MD  more...
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Questions & Answers

Overview

What is myxedema?

What is myxedema coma (crisis)?

What is the pathogenesis of myxedema coma (crisis)?

What is the cardiovascular pathophysiology of myxedema coma (crisis)?

What is the neurologic pathophysiology of myxedema coma (crisis)?

What is the pulmonary pathophysiology of myxedema coma (crisis)?

What is the renal pathophysiology of myxedema coma (crisis)?

What is the GI pathophysiology of myxedema coma (crisis)?

What is the hematologic pathophysiology of myxedema coma (crisis)?

What is the prevalence of myxedema coma (crisis) in the US?

What is the global incidence of myxedema coma (crisis)?

What is the prognosis of myxedema coma (crisis)?

What information about myxedema coma (crisis) should patients be given?

Presentation

What are the signs and symptoms of myxedema coma (crisis)?

What are precipitating factors of myxedema coma (crisis)?

Which physical findings are characteristic of myxedema coma (crisis)?

What are possible complications of myxedema coma (crisis)?

DDX

What are the differential diagnoses for Myxedema Coma or Crisis?

Workup

What is the role of lab studies in the workup of myxedema coma (crisis)?

What is the role of thyroid function tests in the workup of myxedema coma (crisis)?

What is the role of adrenal function assessment in the workup of myxedema coma (crisis)?

Which lab findings suggest myxedema coma (crisis)?

Which tools may be helpful in the diagnosis of myxedema coma (crisis)?

What is the role of chest radiography in the workup of myxedema coma (crisis)?

What is the role of ECG in the workup of myxedema coma (crisis)?

Treatment

What care should be given prior to confirmation of a myxedema coma (crisis) diagnosis?

What is the role of mechanical ventilation in the treatment of myxedema coma (crisis)?

What is the role of thyroid hormone therapy in the treatment of myxedema coma (crisis)?

What is the role of glucocorticoid therapy in the treatment of myxedema coma (crisis)?

What supportive measures are included in the treatment of myxedema coma (crisis)?

When is surgery indicated in the treatment of myxedema coma (crisis)?

Which specialists should be consulted in the treatment of myxedema coma (crisis)?

Which dietary modifications are needed during the treatment of myxedema coma (crisis)?

What activity modifications are needed during the treatment of myxedema coma (crisis)?

How is myxedema coma (crisis) prevented?

What long-term monitoring is needed following treatment of myxedema coma (crisis)?

Medications

What are the goals of drug treatment for myxedema coma (crisis)?

How are thyroid hormones used for the treatment of myxedema coma (crisis)?

How is liothyronine used for the treatment of myxedema coma (crisis)?

How are corticosteroids used to treat myxedema coma (crisis)?

Which medications in the drug class Corticosteroids are used in the treatment of Myxedema Coma or Crisis?

Which medications in the drug class Thyroid hormones are used in the treatment of Myxedema Coma or Crisis?