Type III Polyglandular Autoimmune Syndrome Medication

Updated: Sep 22, 2017
  • Author: KoKo Aung, MD, MPH, FACP; Chief Editor: Romesh Khardori, MD, PhD, FACP  more...
  • Print
Medication

Medication Summary

The goals of pharmacotherapy are to correct hormone deficiencies, prevent complications, and reduce morbidity.

Next:

Thyroid hormones

Class Summary

These agents are administered for replacement of thyroid hormone in hypothyroidism.

Levothyroxine (Synthroid, Levoxyl, Levothroid)

Rapidly inhibits the release of thyroid hormones via a direct effect on the thyroid gland and inhibits the synthesis of thyroid hormones. Iodide also appears to attenuate the cAMP-mediated effects of thyrotropin. In active form, influences growth and maturation of tissues. Involved in normal growth, metabolism, and development.

Previous
Next:

Antidiabetic agents

Class Summary

Insulin is used for replacement therapy in IMD.

Insulin regular human (Novolin, Humulin, Lente Iletin, Lente L, NPH Insulin)

Stimulates proper use of glucose by cells and reduces blood sugar levels. Multiple forms of insulin with different time constants for activity, from very rapid onset and activity to very long sustained activity, can be used to provide glucose control.

Previous
Next:

Vitamins

Class Summary

Vitamins are essential for normal DNA synthesis and for replacement therapy with vitamin B-12 in PA.

Cyanocobalamin (Nascobal, Crystamine, Crysti 1000, Cyomin)

Deoxyadenosylcobalamin and hydroxocobalamin are active forms of vitamin B-12 in humans. Vitamin B-12 synthesized by microbes but not humans or plants.

Previous