Postradiation Sarcoma Questions & Answers

Updated: Jul 01, 2020
  • Author: Nagarjun Rao, MD, FRCPath; Chief Editor: Omohodion (Odion) Binitie, MD  more...
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Questions & Answers

Overview

What is postradiation sarcoma (PRS)?

What are the diagnostic criteria for postradiation sarcoma (PRS)?

What is the pathophysiology of postradiation sarcoma (PRS)?

What causes postradiation sarcoma (PRS)?

What is the prevalence of postradiation sarcoma (PRS)?

Which patient groups have the highest prevalence of postradiation sarcoma (PRS)?

What is the prognosis of postradiation sarcoma (PRS)?

Presentation

Which clinical history findings are characteristic of postradiation sarcoma (PRS)?

Which physical findings are characteristic of postradiation sarcoma (PRS)?

What are the possible complications of postradiation sarcoma (PRS)?

DDX

Which conditions are included in the differential diagnoses of postradiation sarcoma (PRS)?

How is postradiation sarcoma (PRS) differentiated from arthritis?

What are the differential diagnoses for Postradiation Sarcoma?

Workup

What is the role of lab testing in the workup of postradiation sarcoma (PRS)?

What is the role of imaging studies in the workup of postradiation sarcoma (PRS)?

What is the role of biopsy in the workup of postradiation sarcoma (PRS)?

Which histologic findings are characteristic of postradiation sarcoma (PRS)?

How is postradiation sarcoma (PRS) staged?

What are the American Joint Committee on Cancer (AJCC) staging system for postradiation sarcoma (PRS)?

What are the American Joint Committee on Cancer (AJCC) T categories of postradiation sarcoma (PRS)?

What are the American Joint Committee on Cancer (AJCC) N categories of postradiation sarcoma (PRS)?

What are the American Joint Committee on Cancer (AJCC) M categories of postradiation sarcoma (PRS)?

What are the American Joint Committee on Cancer (AJCC) G categories of postradiation sarcoma (PRS)?

What is the Musculoskeletal Tumor Society (MSTS) staging system for postradiation sarcoma (PRS)?

Treatment

How is postradiation sarcoma (PRS) treated?

What is the role of chemotherapy in the treatment of postradiation sarcoma (PRS)?

What is the role of surgery in the treatment of postradiation sarcoma (PRS)?

Which dietary modifications are used in the treatment of postradiation sarcoma (PRS)?

Which activity modifications are used in the treatment of postradiation sarcoma (PRS)?

How is postradiation sarcoma (PRS) prevented?

Which specialist consultations are beneficial to patients with postradiation sarcoma (PRS)?

What is included in long-term monitoring of postradiation sarcoma (PRS)?