Primary (Malignant) Lymphoma of Bone Differential Diagnoses

Updated: Oct 29, 2018
  • Author: Vincent Y Ng, MD; Chief Editor: Harris Gellman, MD  more...
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Diagnostic Considerations

Differential diagnosis based on radiographic examination, depending on a lesion's exact radiographic appearance and on the age of the patient, includes the following:

  • Metastatic carcinoma
  • Osteosarcoma
  • Ewing sarcoma [10]
  • Malignant fibrous histiocytoma or fibrosarcoma of bone
  • Neuroblastoma and other small round cell tumors
  • Langerhans cell histiocytosis
  • Multiple myeloma
  • Leukemic infiltrate
  • Giant cell tumor

Differential Diagnoses