Primary (Malignant) Lymphoma of Bone Questions & Answers

Updated: Oct 29, 2018
  • Author: Vincent Y Ng, MD; Chief Editor: Harris Gellman, MD  more...
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Questions & Answers

Overview

What is primary (malignant) lymphoma of bone (PLB)?

How is primary (malignant) lymphoma of bone (PLB) defined?

What are the most common sites of primary (malignant) lymphoma of bone (PLB)?

What causes primary (malignant) lymphoma of bone (PLB)?

What is the role of genetics in the etiology of primary (malignant) lymphoma of bone (PLB)?

What is the prevalence of primary (malignant) lymphoma of bone (PLB)?

What is the prognosis of primary (malignant) lymphoma of bone (PLB)?

Presentation

Which clinical history findings are characteristic of primary (malignant) lymphoma of bone (PLB)?

Which physical findings are characteristic of primary (malignant) lymphoma of bone (PLB)?

DDX

Which conditions are included in the differential diagnoses of primary (malignant) lymphoma of bone (PLB)?

What are the differential diagnoses for Primary (Malignant) Lymphoma of Bone?

Workup

What is the role of lab testing in the workup of primary (malignant) lymphoma of bone (PLB)?

What is the role of plain radiography in the workup of primary (malignant) lymphoma of bone (PLB)?

What is the role of MRI in the workup of primary (malignant) lymphoma of bone (PLB)?

What is the role of bone scanning in the workup of primary (malignant) lymphoma of bone (PLB)?

What is the role of biopsy in the workup of primary (malignant) lymphoma of bone (PLB)?

How is primary (malignant) lymphoma of bone (PLB) categorized?

Which histologic findings are characteristic of primary (malignant) lymphoma of bone (PLB)?

How is primary (malignant) lymphoma of bone (PLB) staged?

Treatment

How is primary (malignant) lymphoma of bone (PLB) treated?

What is the role of surgery in the treatment of primary (malignant) lymphoma of bone (PLB)?

What is the role of prophylactic stabilization of impending pathologic fractures in the treatment of primary (malignant) lymphoma of bone (PLB)?

How are pathologic fractures treated in primary (malignant) lymphoma of bone (PLB)?

How is spinal involvement in primary (malignant) lymphoma of bone (PLB) treated?

What are contraindications for surgery to treat primary (malignant) lymphoma of bone (PLB)?

What are the possible complications of primary (malignant) lymphoma of bone (PLB) and its treatment?