Osteosarcoma Questions & Answers

Updated: Dec 04, 2018
  • Author: Charles T Mehlman, DO, MPH; Chief Editor: Omohodion (Odion) Binitie, MD  more...
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Questions & Answers

Overview

What is osteosarcoma?

What are the most common sites of osteosarcoma?

What causes osteosarcoma?

What are the racial predilections of osteosarcoma?

What are the sexual predilections of osteosarcoma?

Which age groups have the highest prevalence of osteosarcoma?

What are the survival rates of osteosarcoma?

What is the prognosis of osteosarcoma?

Presentation

Which clinical history findings are characteristic of osteosarcoma?

Which physical findings are characteristic of osteosarcoma?

Workup

What is the role of lab testing in the workup of osteosarcoma?

What is the role of plain radiography in the workup of osteosarcoma?

What is the role of bone scanning in the workup of osteosarcoma?

What is the role of CT scanning in the workup of osteosarcoma?

What is the role of MRI in the workup of osteosarcoma?

What is the role of echocardiography in the workup of osteosarcoma?

What is the role of audiography in the workup of osteosarcoma?

What is included in the histologic exam of osteosarcoma?

What are the histologic types of osteosarcoma?

How is osteosarcoma staged?

What is the Enneking staging system for osteosarcoma?

What is the WBB staging system for osteosarcoma?

Which factors affect the prognosis of osteosarcoma?

What are the staging guidelines for osteosarcoma?

Treatment

What is the role of genetics in the treatment of osteosarcoma?

How is osteosarcoma treated?

What are the contraindications to surgery for osteosarcoma?

How is metastatic or locally recurrent osteosarcoma treated?

Which organizations have issued guidelines on the treatment of osteosarcoma?

What is the role of chemotherapy in the treatment of osteosarcoma?

What is the role of biopsy in the treatment of osteosarcoma?

What is the role of limb-salvage reconstruction in the treatment of osteosarcoma?

What is the role of resection in the treatment of osteosarcoma?

What is the role of surgery in the treatment of metastatic osteosarcoma?

What are the possible complications of osteosarcoma?

Which activity modifications are used in the treatment of osteosarcoma?

Which specialist consultations are beneficial to patients with osteosarcoma?

What is included in inpatient care for osteosarcoma?

What is included in long-term monitoring of osteosarcoma?

Guidelines

Which organizations have published guidelines on osteosarcoma?

What are the NCCN and ESMO treatment guidelines for stage IA-IB osteosarcoma?

What are the NCCN treatment guidelines for stages IIA-IVB osteosarcoma?

What are the NCCN and ESMO treatment guidelines for metastatic osteosarcoma at presentation?

What are the NCCN and ESMO treatment guidelines for relapsed or refractory osteosarcoma?

What are the NCCN and ESMO guidelines for first-line chemotherapy regimens for osteosarcoma?

What are the NCCN guidelines for second-line chemotherapy regimens for osteosarcoma?