Multiple Epiphyseal Dysplasia Differential Diagnoses

Updated: Dec 13, 2021
  • Author: Ashish S Ranade, MBBS, MS, FRCS(Glasg); Chief Editor: Jeffrey D Thomson, MD  more...
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Diagnostic Considerations

Other conditions to be considered in the diagnosis include the following:

  • Bilateral Legg-Calvé-Perthes disease - Patients with this condition may have normal stature; features of multiple epiphyseal dysplasia (MED) include coxa vara with a short and widened femoral neck; in addition, the femoral head is fragmented and flat, and the acetabulum may be involved in patients with MED
  • Pseudoachondroplasia - Features of pseudoachondroplasia include marked ligamentous laxity and pes planovalgus in addition to short stature
  • Spondyloepiphyseal dysplasia (SED) - Typical features of SED are spinal involvement, short stature, and involvement of the hands and feet; SED may also involve the eyes and lungs, and neurologic signs may be noted

Differential Diagnoses