Orthopedic Surgery for Friedreich Ataxia Differential Diagnoses

Updated: Nov 22, 2022
  • Author: Stephen Kishner, MD, MHA; Chief Editor: Vinod K Panchbhavi, MD, FACS, FAOA, FABOS, FAAOS  more...
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Diagnostic Considerations

Other problems to be considered include the following:

  • Hereditary motor and sensory neuropathy (HMSN) type 1
  • Abetalipoproteinemia
  • Other early onset ataxias (ie, Marinesco-Sjögren syndrome, Ramsay Hunt syndrome, X-linked inherited ataxia)
  • Late-onset ataxias (ie, common autosomal dominant cerebellar ataxia [ADCA], Machado-Joseph disease, Cuban and other forms of ADCA, Sporadic cerebellar ataxia of late onset)
  • Developmental ataxias (ie, Dandy-Walker syndrome and Chiari malformation, Joubert syndrome, Gillespie syndrome)
  • Acquired ataxias (ie, trauma, infections [eg, viral including Epstein-Barr virus, echovirus, coxsackievirus, polio virus, Creutzfeldt-Jakob disease, AIDS, toxoplasmosis, Lyme disease, mycoplasma, legionellosis, bacterial abscess], vascular, neoplasms, neoplastic syndromes, demyelinating, metabolic [eg, hyponatremia, hypothyroidism, nutritional], toxins [eg, anticonvulsants, lithium, bismuth, cytotoxic drugs, solvents, methyl mercury, alcohol-related cerebellar degeneration], physical agents [eg, heatstroke])