Venous Thromboembolism (VTE) Differential Diagnoses

Updated: Dec 20, 2021
  • Author: Vera A De Palo, MD, MBA, FCCP; Chief Editor: Vinod K Panchbhavi, MD, FACS, FAOA, FABOS, FAAOS  more...
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Diagnostic Considerations

Conditions that should be differentiated from deep vein thrombosis (DVT) include the following:

  • Cellulitis
  • Ruptured Baker cyst
  • Arterial insufficiency
  • Hematoma
  • Trauma
  • Muscle strain
  • Arthritis
  • Tendonitis
  • Iliac vein compression
  • Lymphedema
  • Sciatic nerve compression

Congestive heart failure (CHF), acute respiratory distress syndrome (ARDS), pulmonary infection, acute pulmonary hypertension, myocardial infarction (MI), cardiac tamponade, and right-side heart failure should be included in the differential diagnoses of shortness of breath and hypoxemia and should be differentiated from pulmonary embolism (PE).