Adrenal Hemorrhage Differential Diagnoses

Updated: Sep 30, 2022
  • Author: Nicholas A Tritos, MD, DSc, MMSc, FACP, FACE; Chief Editor: George T Griffing, MD  more...
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Diagnostic Considerations

Spontaneous adrenal hemorrhage may occur in otherwise uncomplicated pregnancy in the absence of preeclampsia, trauma, or sepsis. Thus, adrenal hemorrhage should be considered in the differential diagnosis of abdominal or flank pain in pregnant women. [11]

A study by Diolombi et al indicated that the diagnosis of adrenocortical adenomas can be difficult in the setting of diffuse (>25%) hemorrhage of the adrenal glands, because malignancy and hemorrhage each cause marked adrenal enlargement. [23]

The aforementioned study by Karwacka et al found that in 16 of the 23 adrenal hemorrhage patients (69.6%), workup revealing the condition stemmed from the discovery of adrenal incidentalomas. [19]

Differential Diagnoses