Low HDL Cholesterol (Hypoalphalipoproteinemia) Questions & Answers

Updated: Nov 03, 2016
  • Author: Vibhuti N Singh, MD, MPH, FACC, FSCAI; Chief Editor: George T Griffing, MD  more...
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Questions & Answers

Overview

What is low HDL cholesterol (hypoalphalipoproteinemia)?

What is the role of plasma lipoproteins in the pathophysiology of low HDL cholesterol (hypoalphalipoproteinemia)?

What is the pathophysiology of familial low HDL cholesterol (hypoalphalipoproteinemia)?

What is the pathophysiology of familial LCAT deficiency?

What is the pathophysiology of Tangier disease?

What is the role of plasma HDL in the pathophysiology of low HDL cholesterol (hypoalphalipoproteinemia)?

What is the reverse cholesterol transport system in the pathophysiology of low HDL cholesterol (hypoalphalipoproteinemia)?

What are the variants of low HDL cholesterol (hypoalphalipoproteinemia)?

What is the US prevalence of low HDL cholesterol (hypoalphalipoproteinemia)?

What is the global prevalence of low HDL cholesterol (hypoalphalipoproteinemia)?

What is the mortality and morbidity associated with low HDL cholesterol (hypoalphalipoproteinemia)?

What are the racial predilections of low HDL cholesterol (hypoalphalipoproteinemia)?

What are the sexual predilections of low HDL cholesterol (hypoalphalipoproteinemia)?

Presentation

Which clinical history findings are associated with secondary causes of low HDL cholesterol (hypoalphalipoproteinemia)?

Which clinical history findings are characteristic of low HDL cholesterol (hypoalphalipoproteinemia)?

Which physical findings are characteristic of low HDL cholesterol (hypoalphalipoproteinemia)?

What are the primary or familial causes of low HDL cholesterol (hypoalphalipoproteinemia)?

What are the secondary causes of low HDL cholesterol (hypoalphalipoproteinemia)?

What causes low HDL cholesterol (hypoalphalipoproteinemia)?

Workup

What is the role of lab tests in the workup of low HDL cholesterol (hypoalphalipoproteinemia)?

What is the role of imaging studies in the workup of low HDL cholesterol (hypoalphalipoproteinemia)?

Which specialized lab tests may be included in the workup of low HDL cholesterol (hypoalphalipoproteinemia)?

What is the role of cardiac testing in the workup of low HDL cholesterol (hypoalphalipoproteinemia)?

How are patients with low HDL cholesterol (hypoalphalipoproteinemia) monitored for premature atherosclerosis?

Which histologic findings are characteristic of low HDL cholesterol (hypoalphalipoproteinemia)?

Treatment

What are the guidelines in the ATP III report on management of low HDL cholesterol (hypoalphalipoproteinemia)?

Which HDL-raising therapies are used in the treatment of low HDL cholesterol (hypoalphalipoproteinemia)?

What is the role of niacin, fibrates and statins in the treatment of low HDL cholesterol (hypoalphalipoproteinemia)?

What were the results of the ADVOCATE study on cholesterol-modulating agents for the treatment of low HDL cholesterol (hypoalphalipoproteinemia)?

What is the efficacy of combined niacin/statin for the treatment of low HDL cholesterol (hypoalphalipoproteinemia)?

Which medications are being investigated as possible treatments for low HDL cholesterol (hypoalphalipoproteinemia)?

What is the role of CETP inhibition therapy in the treatment of low HDL cholesterol (hypoalphalipoproteinemia)?

How are low HDL cholesterol (hypoalphalipoproteinemia) variants treated?

What is the role of surgery in the treatment of low HDL cholesterol (hypoalphalipoproteinemia)?

Which specialist consultations are beneficial to patients with low HDL cholesterol (hypoalphalipoproteinemia)?

Which dietary modifications are used in the treatment of low HDL cholesterol (hypoalphalipoproteinemia)?

Which activity modifications are used in the treatment of low HDL cholesterol (hypoalphalipoproteinemia)?

Medications

What is the role of medications in the treatment of low HDL cholesterol (hypoalphalipoproteinemia)?

Which medications in the drug class HMG-CoA reductase inhibitors are used in the treatment of Low HDL Cholesterol (Hypoalphalipoproteinemia)?

Which medications in the drug class Antilipemic agents are used in the treatment of Low HDL Cholesterol (Hypoalphalipoproteinemia)?

Follow-up

What is included in the long-term monitoring of low HDL cholesterol (hypoalphalipoproteinemia)?

When is inpatient care indicated for the treatment of low HDL cholesterol (hypoalphalipoproteinemia)?

Which medications are used in the treatment of low HDL cholesterol (hypoalphalipoproteinemia)?

When is patient transfer indicated for the treatment of low HDL cholesterol (hypoalphalipoproteinemia)?

How is low HDL cholesterol (hypoalphalipoproteinemia) prevented?

What are the possible complications of low HDL cholesterol (hypoalphalipoproteinemia)?

What is the prognosis of low HDL cholesterol (hypoalphalipoproteinemia)?

What is included in patient education about low HDL cholesterol (hypoalphalipoproteinemia)?