Medical Care

Because congenital self-healing reticulohistiocytosis is a self-limited disorder that is asymptomatic, no specific treatment is required.

Consultations

Consultation with a pediatric dermatologist may be required to confirm the diagnosis. Consultation with a pediatric hematologist/oncologist is important in the systemic evaluation of the patient.

Long-Term Monitoring

Congenital self-healing reticulohistiocytosis patients must be evaluated at regular intervals for signs of progression or recurrence. Any signs of extracutaneous involvement must be investigated. Long-term follow up may include laboratory studies and other tests included in the initial evaluation.

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Media Gallery

Urticarial patches on the leg of a 3-month-old infant and several reddish-brown papules on the foot typical of congenital self-healing reticulohistiocytosis.
Reddish-brown papules of congenital self-healing reticulohistiocytosis on the foot of a 3-month-old infant.
Hematoxylin and eosin–stained section (400X) showing hemorrhage and infiltration of papillary dermis and epidermis with mononuclear and histiocytic (Langerhans) cells with reniform nuclei.
Hematoxylin and eosin–stained section (400X) showing an intraepidermal collection of histiocytic (Langerhans) cells with prominent reniform nuclei.
Immunohistochemical staining with CD-1a shows positive staining of cells within intraepidermal microabscesses.
Electron microscopy demonstrating cytoplasmic Birbeck (tennis racket) granules.

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Author

David F Butler, MD Former Section Chief of Dermatology, Central Texas Veterans Healthcare System; Professor of Dermatology, Texas A&M University College of Medicine; Founding Chair, Department of Dermatology, Scott and White Clinic

David F Butler, MD is a member of the following medical societies: Alpha Omega Alpha, American Academy of Dermatology, Association of Military Dermatologists, Phi Beta Kappa, Texas Dermatological Society

Disclosure: Nothing to disclose.

Specialty Editor Board

Richard P Vinson, MD Assistant Clinical Professor, Department of Dermatology, Texas Tech University Health Sciences Center, Paul L Foster School of Medicine; Consulting Staff, Mountain View Dermatology, PA

Richard P Vinson, MD is a member of the following medical societies: American Academy of Dermatology, Texas Medical Association, Association of Military Dermatologists, Texas Dermatological Society

Disclosure: Nothing to disclose.

Rosalie Elenitsas, MD Herman Beerman Professor of Dermatology, University of Pennsylvania School of Medicine; Director, Penn Cutaneous Pathology Services, Department of Dermatology, University of Pennsylvania Health System

Rosalie Elenitsas, MD is a member of the following medical societies: American Academy of Dermatology, American Medical Association, American Society of Dermatopathology, Pennsylvania Academy of Dermatology

Disclosure: Received royalty from Lippincott Williams Wilkins for textbook editor.

Chief Editor

Dirk M Elston, MD Professor and Chairman, Department of Dermatology and Dermatologic Surgery, Medical University of South Carolina College of Medicine

Dirk M Elston, MD is a member of the following medical societies: American Academy of Dermatology

Disclosure: Nothing to disclose.

Additional Contributors

Jacek C Szepietowski, MD, PhD Professor, Vice-Head, Department of Dermatology, Venereology and Allergology, Wroclaw Medical University; Director of the Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Poland

Disclosure: Received consulting fee from Orfagen for consulting; Received consulting fee from Maruho for consulting; Received consulting fee from Astellas for consulting; Received consulting fee from Abbott for consulting; Received consulting fee from Leo Pharma for consulting; Received consulting fee from Biogenoma for consulting; Received honoraria from Janssen for speaking and teaching; Received honoraria from Medac for speaking and teaching; Received consulting fee from Dignity Sciences for consulting; .

Acknowledgements

Jessica L Clark, MD Texas A&M University System Health Science Center College of Medicine

Disclosure: Nothing to disclose.