Connective Tissue Disease-Associated Interstitial Lung Disease (CTD-ILD) Differential Diagnoses

Updated: Aug 06, 2020
  • Author: Aniruddh Kapoor, MBBS; Chief Editor: Zab Mosenifar, MD, FACP, FCCP  more...
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Diagnostic Considerations

As previously mentioned, a multidisciplinary approach to the diagnosis and treatment of connective tissue disease-associated interstitial lung disease (CTD-ILD) is of paramount importance. A thorough history and physical examination should be supplemented by chest radiography, serum biomarkers and, occasionally, histopathology.

It is essential to make an effort to exclude the diagnosis of underlying CTD or interstitial pneumonia with autoimmune features (IPAF) in a patient presenting with ILD, as previous data have shown improved outcomes regardless of the histopathologic diagnosis. [9, 45]

Differential Diagnoses