Brachioradial Pruritus Questions & Answers

1. Heyl T. Brachioradial pruritus. Arch Dermatol. 1983 Feb. 119(2):115-6. [QxMD MEDLINE Link].

2. Veien NK, Hattel T, Laurberg G, Spaun E. Brachioradial pruritus. J Am Acad Dermatol. 2001 Apr. 44(4):704-5. [QxMD MEDLINE Link].

3. Bernhard JD, Bordeaux JS. Medical pearl: the ice-pack sign in brachioradial pruritus. J Am Acad Dermatol. 2005 Jun. 52(6):1073. [QxMD MEDLINE Link].

4. Waisman M. Solar pruritus of the elbows (brachioradial summer pruritus). Arch Dermatol. 1968 Nov. 98(5):481-5. [QxMD MEDLINE Link].

5. Walcyk PJ, Elpern DJ. Brachioradial pruritus: a tropical dermopathy. Br J Dermatol. 1986 Aug. 115(2):177-80. [QxMD MEDLINE Link].

6. Robbins BA, Schmieder GJ. Brachioradial Pruritus. StatPearls [Internet]. 2020 Jan. [QxMD MEDLINE Link]. [Full Text].

7. Shumway NK, Cole E, Fernandez KH. Neurocutaneous disease: Neurocutaneous dysesthesias. J Am Acad Dermatol. 2016 Feb. 74 (2):215-28; quiz 229-30. [QxMD MEDLINE Link].

8. Massey EW, Massey JM. Forearm neuropathy and pruritus. South Med J. 1986 Oct. 79(10):1259-60. [QxMD MEDLINE Link].

9. Crevits L. Brachioradial pruritus--a peculiar neuropathic disorder. Clin Neurol Neurosurg. 2006 Dec. 108(8):803-5. [QxMD MEDLINE Link].

10. Fisher DA. Brachioradial pruritus wanted: a sure cause (and cure) for brachioradial pruritus. Int J Dermatol. 1997 Nov. 36(11):817-8. [QxMD MEDLINE Link].

11. Binder A, Folster-Holst R, Sahan G. et al. A case of neuropathic brachioradial pruritus caused by cervical disc herniation. Nat Clin Pract Neurol. June 2008. 4 (6):338-342. [QxMD MEDLINE Link]. [Full Text].

12. Wallengren J, Sundler F. Brachioradial pruritus is associated with a reduction in cutaneous innervation that normalizes during the symptom-free remissions. J Am Acad Dermatol. 2005 Jan. 52(1):142-5. [QxMD MEDLINE Link].

13. Wallengren J. Self-healing photo-neuropathy and cervical spinal arthrosis in four sisters with brachioradial pruritus. J Brachial Plex Peripher Nerve Inj. November 2009. 17; 4:21. [QxMD MEDLINE Link]. [Full Text].

14. De Ridder D, Hans G, Pals P, Menovsky T. A C-fiber-mediated neuropathic brachioradial pruritus. J Neurosurg. October 2009. 1-4. [QxMD MEDLINE Link]. [Full Text].

15. Wallengren J, Dahlbäck K. Familial brachioradial pruritus. Br J Dermatol. 2005 Nov. 153(5):1016-8. [QxMD MEDLINE Link].

16. Bech-Thomsen N, Thomsen K. Solar pruritus. Acta Derm Venereol. 1995 Nov. 75(6):488-9. [QxMD MEDLINE Link].

17. Kestenbaum T, Kalivas J. Solar pruritus. Arch Dermatol. 1979 Nov. 115(11):1368. [QxMD MEDLINE Link].

18. Orton DI, Wakelin SH, George SA. Brachioradial photopruritus--a rare chronic photodermatosis in Europe. Br J Dermatol. 1996 Sep. 135(3):486-7. [QxMD MEDLINE Link].

19. Armstrong DK, Bingham EA. Brachioradial pruritus--an uncommon photodermatosis presenting in a temperate climate. Dermatology. 1997. 195(4):414-5. [QxMD MEDLINE Link].

20. Masuda PY, Martelli AC, Wachholz PA, Akumatsu HT, Martins AL, Silva NM. Brachioradial pruritus -- descriptive analysis of Brazilian case series. J Dtsch Dermatol Ges. 2013 Jun. 11(6):530-5. [QxMD MEDLINE Link].

21. Zabludovska K, Anderson MD, Jemec GB. Photoallergic reactions to varenicline mimicking brachioradial pruritus. J Am Acad Dermatol. 2013 Sep. 69(3):484. [QxMD MEDLINE Link].

22. Barry R, Rogers S. Brachioradial pruritus--an enigmatic entity. Clin Exp Dermatol. 2004 Nov. 29(6):637-8. [QxMD MEDLINE Link].

23. Goodkin R, Wingard E, Bernhard JD. Brachioradial pruritus: cervical spine disease and neurogenic/neuropathic [corrected] pruritus. J Am Acad Dermatol. 2003 Apr. 48(4):521-4. [QxMD MEDLINE Link].

24. Marziniak M, Phan NQ, Raap U, Siepmann D, Schürmeyer-Horst F, Pogatzki-Zahn E, et al. Brachioradial pruritus as a result of cervical spine pathology: the results of a magnetic resonance tomography study. J Am Acad Dermatol. 2011 Oct. 65(4):756-62. [QxMD MEDLINE Link].

25. Tait CP, Grigg E, Quirk CJ. Brachioradial pruritus and cervical spine manipulation. Australas J Dermatol. 1998 Aug. 39(3):168-70. [QxMD MEDLINE Link].

26. Kavak A, Dosoglu M. Can a spinal cord tumor cause brachioradial pruritus?. J Am Acad Dermatol. 2002 Mar. 46(3):437-40. [QxMD MEDLINE Link].

27. Rongioletti F. Pruritus as presenting sign of cervical rib. Lancet. 1992 Jan 4. 339(8784):55. [QxMD MEDLINE Link].

28. Lane JE, McKenzie JT, Spiegel J. Brachioradial pruritus: a case report and review of the literature. Cutis. January 2008. 81(1):37-40. [QxMD MEDLINE Link].

29. Cohen AD, Masalha R, Medvedovsky E, Vardy DA. Brachioradial pruritus: a symptom of neuropathy. J Am Acad Dermatol. 2003 Jun. 48(6):825-8. [QxMD MEDLINE Link].

30. Gore DR, Sepic SB, Gardner GM. Roentgenographic findings of the cervical spine in asymptomatic people. Spine. 1986 Jul-Aug. 11(6):521-4. [QxMD MEDLINE Link].

31. Savk E, Savk SO. On brachioradial pruritus and notalgia paresthetica. J Am Acad Dermatol. 2004 May. 50(5):800-1. [QxMD MEDLINE Link].

32. Mirzoyev SA, Davis MD. Brachioradial pruritus: Mayo Clinic experience over the past decade. Br J Dermatol. 2013 Nov. 169(5):1007-15. [QxMD MEDLINE Link].

33. Kanitakis J. Brachioradial pruritus: report of a new case responding to gabapentin. Eur J Dermatol. 2006 May-Jun. 16(3):311-2. [QxMD MEDLINE Link].

34. Kwatra SG, Stander S, Bernhard JD, Weisshaar E, Yosipovitch G. Brachioradial pruritus: a trigger for generalization of itch. J Am Acad Dermatol. 2013 May. 68(5):870-3. [QxMD MEDLINE Link].

35. Skelton F, Frontera JE. Brachioradial Pruritus as a Harbinger of Syrinx in Chronic Spinal Cord Injury: A Case Report. PM R. 2017 Mar. 9 (3):311-313. [QxMD MEDLINE Link].

36. Wachholz PA, Masuda PY, Pinto ACVD, Martelli ACC. Impact of drug therapy on brachioradial pruritus. An Bras Dermatol. 2017 Mar-Apr. 92 (2):281-282. [QxMD MEDLINE Link].

37. Atış G, Bilir Kaya B. Pregabalin treatment of three cases with brachioradial pruritus. Dermatol Ther. 2017 Mar. 30 (2):[QxMD MEDLINE Link].

38. Vestita M, Cerbone L, Calista D. Brachioradial pruritus in a 47-year-old woman treated with pregabalin. G Ital Dermatol Venereol. 2016 Dec. 151 (6):727-728. [QxMD MEDLINE Link].

39. Pinto AC, Wachholz PA, Masuda PY, Martelli AC. Clinical, epidemiological and therapeutic profile of patients with brachioradial pruritus in a reference service in dermatology. An Bras Dermatol. 2016 Jul-Aug. 91 (4):549-51. [QxMD MEDLINE Link].

40. Wallengren J, Sundler F. Cutaneous field stimulation in the treatment of severe itch. Arch Dermatol. 2001 Oct. 137(10):1323-5. [QxMD MEDLINE Link].

41. Stellon A. Neurogenic pruritus: an unrecognised problem? A retrospective case series of treatment by acupuncture. Acupunct Med. 2002 Dec. 20(4):186-90. [QxMD MEDLINE Link].

42. Kavanagh GM, Tidman MJ. Botulinum A toxin and brachioradial pruritus. Br J Dermatol. 2012 May. 166(5):1147. [QxMD MEDLINE Link].

43. Poterucha TJ, Murphy SL, Davis MD, Sandroni P, Rho RH, Warndahl RA, et al. Topical amitriptyline-ketamine for the treatment of brachioradial pruritus. JAMA Dermatol. 2013 Feb. 149(2):148-50. [QxMD MEDLINE Link].

44. Magazin M, Daze RP, Okeson N. Treatment Refractory Brachioradial Pruritus Treated with Topical Amitriptyline and Ketamine. Cureus. 2019 Jul 10. 11 (7):e5117. [QxMD MEDLINE Link].

45. Ally MS, Gamba CS, Peng DH, Tang JY. The use of aprepitant in brachioradial pruritus. JAMA Dermatol. 2013 May. 149(5):627-8. [QxMD MEDLINE Link].

46. He A, Alhariri JM, Sweren RJ, Kwatra MM, Kwatra SG. Aprepitant for the Treatment of Chronic Refractory Pruritus. Biomed Res Int. 2017. 2017:4790810. [QxMD MEDLINE Link].

47. Bernstein JE. Capsaicin and substance P. Clin Dermatol. 1991 Oct-Dec. 9(4):497-503. [QxMD MEDLINE Link].

48. Goodless DR, Eaglstein WH. Brachioradial pruritus: treatment with topical capsaicin. J Am Acad Dermatol. 1993 Nov. 29(5 Pt 1):783-4. [QxMD MEDLINE Link].

49. Knight TE, Hayashi T. Solar (brachioradial) pruritus--response to capsaicin cream. Int J Dermatol. 1994 Mar. 33(3):206-9. [QxMD MEDLINE Link].

50. Zeidler C, Lüling H, Dieckhöfer A, Osada N, Schedel F, Steinke S, et al. Capsaicin 8% cutaneous patch: a promising treatment for brachioradial pruritus?. Br J Dermatol. 2015 Jun. 172 (6):1669-71. [QxMD MEDLINE Link].

51. Steinke S, Gutknecht M, Zeidler C, Dieckhöfer AM, Herrlein O, Lüling H, et al. Cost-effectiveness of an 8% Capsaicin Patch in the Treatment of Brachioradial Pruritus and Notalgia Paraesthetica, Two Forms of Neuropathic Pruritus. Acta Derm Venereol. 2017 Jan 4. 97 (1):71-76. [QxMD MEDLINE Link].

52. Pereira MP, Lüling H, Dieckhöfer A, Steinke S, Zeidler C, Agelopoulos K, et al. Application of an 8% capsaicin patch normalizes epidermal TRPV1 expression but not the decreased intraepidermal nerve fibre density in patients with brachioradial pruritus. J Eur Acad Dermatol Venereol. 2018 Feb 10. [QxMD MEDLINE Link].

Julianne Mann, MD Assistant Professor, Department of Dermatology, Oregon Health and Science University School of Medicine

Julianne Mann, MD is a member of the following medical societies: Alpha Omega Alpha, Phi Beta Kappa

Disclosure: Nothing to disclose.

David J Elpern, MD Consulting Staff, The Skin Clinic

David J Elpern, MD is a member of the following medical societies: American Academy of Dermatology, Hawaii Medical Association

Disclosure: Nothing to disclose.

Britton R Mann, DAOM, Dip OM, LAc Private Practitioner in Acupuncture and Chinese Herbal Medicine, Metolius Natural Medicine

Disclosure: Nothing to disclose.

David F Butler, MD Former Section Chief of Dermatology, Central Texas Veterans Healthcare System; Professor of Dermatology, Texas A&M University College of Medicine; Founding Chair, Department of Dermatology, Scott and White Clinic

David F Butler, MD is a member of the following medical societies: Alpha Omega Alpha, American Academy of Dermatology, Association of Military Dermatologists, Phi Beta Kappa, Texas Dermatological Society

Disclosure: Nothing to disclose.

Dirk M Elston, MD Professor and Chairman, Department of Dermatology and Dermatologic Surgery, Medical University of South Carolina College of Medicine

Dirk M Elston, MD is a member of the following medical societies: American Academy of Dermatology

Disclosure: Nothing to disclose.

Jacek C Szepietowski, MD, PhD Professor, Vice-Head, Department of Dermatology, Venereology and Allergology, Wroclaw Medical University; Director of the Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Poland

Disclosure: Received consulting fee from Orfagen for consulting; Received consulting fee from Maruho for consulting; Received consulting fee from Astellas for consulting; Received consulting fee from Abbott for consulting; Received consulting fee from Leo Pharma for consulting; Received consulting fee from Biogenoma for consulting; Received honoraria from Janssen for speaking and teaching; Received honoraria from Medac for speaking and teaching; Received consulting fee from Dignity Sciences for consulting; .

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