Wiskott-Aldrich Syndrome Questions & Answers

Updated: Oct 16, 2019
  • Author: Peter N Huynh, MD; Chief Editor: Michael A Kaliner, MD  more...
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Questions & Answers

Overview

What is Wiskott-Aldrich syndrome (WAS)?

What is the pathophysiology of Wiskott-Aldrich syndrome (WAS)?

What is the US prevalence of Wiskott-Aldrich syndrome (WAS)?

What is the global prevalence of Wiskott-Aldrich syndrome (WAS)?

How does Wiskott-Aldrich syndrome (WAS) affect mortality?

What are the racial predilections of Wiskott-Aldrich syndrome (WAS)?

What are the sexual predilections of Wiskott-Aldrich syndrome (WAS)?

At what age is Wiskott-Aldrich syndrome (WAS) typically diagnosed?

What is the prognosis of Wiskott-Aldrich syndrome (WAS)?

What is included in patient education about Wiskott-Aldrich syndrome (WAS)?

What online patient education resources about Wiskott-Aldrich syndrome (WAS) are available?

Presentation

Which clinical history findings are characteristic of Wiskott-Aldrich syndrome (WAS)?

What is included in the physical exam to evaluate for Wiskott-Aldrich syndrome (WAS)?

What causes Wiskott-Aldrich syndrome (WAS)?

What are the possible complications of Wiskott-Aldrich syndrome (WAS)?

DDX

What are the differential diagnoses for Wiskott-Aldrich Syndrome?

Workup

What is the role of lab testing in the workup of Wiskott-Aldrich syndrome (WAS)?

What is the role of imaging studies in the workup of Wiskott-Aldrich syndrome (WAS)?

What is the role of bone marrow biopsy in the workup of Wiskott-Aldrich syndrome (WAS)?

What is the role of lumbar puncture in the workup of Wiskott-Aldrich syndrome (WAS)?

How is recurrent otitis media treated in patients with Wiskott-Aldrich syndrome (WAS)?

Which histologic findings are characteristic of Wiskott-Aldrich syndrome (WAS)?

Treatment

What is the role of gene therapy in the treatment of Wiskott-Aldrich syndrome (WAS)?

How is Wiskott-Aldrich syndrome (WAS) treated?

What is the role of hematopoietic stem cell transplantation (HSCT) in the treatment of Wiskott-Aldrich syndrome (WAS)?

What is the role of surgery in the treatment of Wiskott-Aldrich syndrome (WAS)?

Which specialist consultations are beneficial to patients with Wiskott-Aldrich syndrome (WAS)?

Which dietary modifications are used in the treatment of Wiskott-Aldrich syndrome (WAS)?

Which activity modifications are used in the treatment of Wiskott-Aldrich syndrome (WAS)?

How is Wiskott-Aldrich syndrome (WAS) prevented?

Medications

What is the role of medications in the treatment of Wiskott-Aldrich syndrome (WAS)?

Which medications in the drug class Immunoglobulins are used in the treatment of Wiskott-Aldrich Syndrome?

Which medications in the drug class Corticosteroids are used in the treatment of Wiskott-Aldrich Syndrome?

Follow-up

What is included in the long-term monitoring of Wiskott-Aldrich syndrome (WAS)?

When is inpatient care needed for the treatment of Wiskott-Aldrich syndrome (WAS)?

Which medications are used in the treatment of Wiskott-Aldrich syndrome (WAS)?

When is patient transfer indicated for the treatment of Wiskott-Aldrich syndrome (WAS)?