Immunoglobulin M Deficiency Medication

Updated: Nov 14, 2016
  • Author: Iftikhar Hussain, MD; Chief Editor: Michael A Kaliner, MD  more...
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Medication

Medication Summary

Infections should be treated promptly with appropriate antibiotics, depending on the suspected pathogen. Empiric broad-spectrum therapy may be necessary before specific organisms are isolated. Some patients with selective IgM deficiency may also have increased susceptibility to fungal infections, so excessive use of broad spectrum antibiotics should be avoided, and anti-fungals should be added when appropriate.

Intravenous immunoglobulin is a therapeutic consideration for patients with SIgM deficiency who have demonstrated findings of defective antigen-specific IgG responses, particularly if they lack IgG against encapsulated bacteria and have chronic or recurrent sinopulmonary infection. [26]