Macrophage Activation Syndrome Questions & Answers

Updated: Nov 21, 2018
  • Author: Angelo Ravelli, MD; Chief Editor: Lawrence K Jung, MD  more...
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Questions & Answers

Overview

What is macrophage activation syndrome (MAS)?

What is the pathophysiology of macrophage activation syndrome (MAS)?

What is the US prevalence of macrophage activation syndrome (MAS)?

What is the global prevalence of macrophage activation syndrome (MAS)?

What is the mortality and morbidity associated with macrophage activation syndrome (MAS)?

Which age groups have the highest prevalence of macrophage activation syndrome (MAS)?

Presentation

Which clinical history findings are characteristic of macrophage activation syndrome (MAS)?

Which physical findings are characteristic of macrophage activation syndrome (MAS)?

What causes macrophage activation syndrome (MAS)?

DDX

Which conditions are included in the differential diagnoses of

What are the differential diagnoses for Macrophage Activation Syndrome?

Workup

How is macrophage activation syndrome (MAS) diagnosed?

How is macrophage activation syndrome (MAS) complicating systemic juvenile idiopathic arthritis (SJIA) diagnosed?

How is macrophage activation syndrome (MAS) diagnosed in patients with systemic lupus erythematosus (SLE)?

What is the role of genetic analysis in the workup of macrophage activation syndrome (MAS)?

Which histologic findings are characteristic of macrophage activation syndrome (MAS)?

Treatment

How is macrophage activation syndrome (MAS) treated?

Which specialist consultations are beneficial to patients with macrophage activation syndrome (MAS)?

Follow-up

What is included in the long-term monitoring of macrophage activation syndrome (MAS)?

When is inpatient care indicated for macrophage activation syndrome (MAS)?

When is patient transfer required for the treatment of macrophage activation syndrome (MAS)?

What are the possible complications of macrophage activation syndrome (MAS)?

What is the prognosis of macrophage activation syndrome (MAS)?

Medications

Which medications in the drug class Immunomodulator are used in the treatment of Macrophage Activation Syndrome?

Which medications in the drug class Corticosteroids are used in the treatment of Macrophage Activation Syndrome?