Endomyocardial Fibrosis Differential Diagnoses

Updated: Nov 24, 2014
  • Author: Ali A Sovari, MD, FACP, FACC; Chief Editor: Henry H Ooi, MD, MRCPI  more...
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Diagnostic Considerations

As with other forms of restrictive cardiomyopathy, distinguish endomyocardial fibrosis (EMF) from constrictive pericarditis.

Other conditions to consider in patients with suspected EMF include the following:

  • Anthracycline toxicity
  • Carcinoid heart disease
  • Drug-induced cardiotoxicity (eg, serotonin, methysergide, ergotamine, mercurial agents, busulfan)
  • Fabry disease
  • Fatty infiltration
  • Gaucher disease
  • Glycogen storage disease
  • Hurler disease
  • Idiopathic cardiomyopathy
  • Metastatic cancers
  • Radiation
  • Rheumatic heart disease

Occasionally, a masslike lesion seen in endomyocardial fibrosis masquerades as an intracardiac tumor.

Differential Diagnoses